慢性肝病中乙型肝炎病毒与丙型肝炎病毒合并感染的患病率。
Prevalence of hepatitis B and hepatitis C virus coinfection in chronic liver disease.
作者信息
Xess A, Kumar M, Minz S, Sharma H P, Shahi S K
机构信息
Department of Microbiology, Indira Gandhi Institute of Medical Sciences, Sheikhpura, Patna.
出版信息
Indian J Pathol Microbiol. 2001 Jul;44(3):253-5.
Coinfection with HBV and HCV may lead to serious consequences. The present study was done to find out the prevalence of coinfection in patients with chronic liver disease. From patients with hepatitis and chronic liver disease 1673 samples were received and analysed for HBsAg by ELISA. 1342 samples were analysed for anti HCV by third generation ELISA. 493 samples positive for HBsAg were also analysed for Anti HCV to see the prevalence of coinfection. 15(3.0%) were found positive for both HBsAg and anti HCV. Out of 15 patients with coinfection 4 (26.6%) had HCC. Prevalence of HCC in patients with coinfection was higher than either infection alone i.e. HBV-9.1% and HCV-16.5%.
乙肝病毒（HBV）和丙肝病毒（HCV）合并感染可能会导致严重后果。本研究旨在查明慢性肝病患者中合并感染的流行情况。从患有肝炎和慢性肝病的患者中收集了1673份样本，并通过酶联免疫吸附测定法（ELISA）对乙肝表面抗原（HBsAg）进行分析。通过第三代ELISA对1342份样本进行丙肝抗体（抗HCV）分析。对493份HBsAg呈阳性的样本也进行了抗HCV分析，以了解合并感染的流行情况。发现15份样本（3.0%）的HBsAg和抗HCV均呈阳性。在15例合并感染患者中，4例（26.6%）患有肝癌。合并感染患者中肝癌的患病率高于单独感染乙肝病毒（HBV）（9.1%）或丙肝病毒（HCV）（16.5%）的患者。
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