预防性前房内注射头孢呋辛。预防白内障手术后眼内炎的疗效。
Prophylactic intracameral cefuroxime. Efficacy in preventing endophthalmitis after cataract surgery.
作者信息
Montan Per G, Wejde Gisela, Koranyi Gabor, Rylander Margareta
机构信息
Department of Ophthalmology, St. Eriks Hospital, Stockholm, Sweden.
出版信息
J Cataract Refract Surg. 2002 Jun;28(6):977-81. doi: 10.1016/s0886-3350(01)01269-x.
PURPOSE
To evaluate the efficacy of prophylactic intracameral cefuroxime in preventing endophthalmitis in cataract surgery.
SETTING
Department of Ophthalmology, St. Eriks Hospital, Stockholm, Sweden.
METHODS
In a noncontrolled retrospective observational study, all cases of recorded postoperative endophthalmitis were related to the total number of uncombined cataract procedures from January 1996 to December 2000.
RESULTS
Twenty cases of postoperative endophthalmitis occurred in 32180 procedures, yielding an overall rate of 0.06%. Cefuroxime-resistant organisms accounted for 12 of 13 culture-positive cases, and enterococci were the most common etiology.
CONCLUSIONS
Intracameral cefuroxime 1 mg appeared to effectively inhibit sensitive bacterial strains and was associated with a low frequency of postoperative endophthalmitis. The causative organisms of future incidents of postoperative endophthalmitis will determine whether the present protocol must be reappraised.
目的
评估前房内注射头孢呋辛预防白内障手术眼内炎的疗效。
背景
瑞典斯德哥尔摩圣埃里克医院眼科。
方法
在一项非对照回顾性观察研究中，记录了1996年1月至2000年12月期间所有白内障手术病例中术后眼内炎的发生情况，并与白内障手术总数相关。
结果
32180例手术中发生20例术后眼内炎，总体发生率为0.06%。13例培养阳性病例中有12例为耐头孢呋辛菌，肠球菌是最常见的病因。
结论
1mg前房内注射头孢呋辛似乎能有效抑制敏感菌株，并与术后眼内炎的低发生率相关。未来术后眼内炎事件的病原体将决定是否必须重新评估当前方案。
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