Thorner M O, Besser G M, Jones A, Dacie J, Jones A E
Br Med J. 1975 Dec 20;4(5998):694-7. doi: 10.1136/bmj.4.5998.694.
Thirteen pregnancies occurred in 12 women who were treated with bromocriptine for infertility. Pretreatment prolactin levels were recorded in 11 patients and were normal in three. Five patients had suspected pituitary tumours, and they received irradiation to prevent swelling of the pituitary and the consequent visual field defects caused by the pressure of the swollen gland on the optic nerve. Ten of the 13 pregnancies have come to term, and all the babies were normal. When a patient with a pituitary tumour developed a visual field defect in the 38th week of pregnancy labour was induced and the defect disappeared after delivery. No multiple pregnancies occurred and there were no major complications.
12名因不育接受溴隐亭治疗的女性共怀孕13次。11名患者记录了治疗前的催乳素水平,其中3名正常。5名患者疑似患有垂体瘤,他们接受了放射治疗,以防止垂体肿胀以及肿胀腺体对视神经压迫导致的视野缺损。13次怀孕中有10次足月分娩,所有婴儿均正常。一名患有垂体瘤的患者在怀孕第38周出现视野缺损,随后引产,产后缺损消失。未发生多胎妊娠,也无重大并发症。