Kaplan M L, Garcia D A, Goldhaber P, Davis M A, Adelstein S J
Calcif Tissue Res. 1975 Dec 18;19(2):91-8. doi: 10.1007/BF02563994.
Bone seeking radiopharmaceuticals were used in conjunction with skeletal imaging techniques to study bone mineral metabolism in beagle jaws. In beagles with chronic destructive periodontal disease, the tooth-supporting bone exhibited an increased uptake of technetium-99m-tin-diphosphonate when compared to control dogs. Scan images of soft tissue and vascular pools in the diseased jaws were normal. When quantitative densitometric data derived from bone scan images were compared, it was found that values reflecting radionuclide uptake in dogs with chronic destructive periodontal disease were six times greater than corresponding values in control dogs.
亲骨性放射性药物与骨骼成像技术联合使用，以研究比格犬颌骨的骨矿物质代谢。在患有慢性破坏性牙周病的比格犬中，与对照犬相比，支持牙齿的骨骼对锝-99m-锡-二膦酸盐的摄取增加。患病颌骨的软组织和血管池扫描图像正常。当比较从骨扫描图像得出的定量密度数据时，发现反映患有慢性破坏性牙周病的犬放射性核素摄取的值比对照犬的相应值大六倍。
