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[单侧脑损伤后的记忆障碍]

[Memory disorders after unilateral cerebral lesions].

作者信息

Metzler P, Haas W, Potel C

机构信息

Unfallkrankenhaus Berlin, Klinik für Neurologie mit Stroke Unit und Frührehabilitation, Warener Strasse 7, 12683 Berlin.

出版信息

Nervenarzt. 2002 Apr;73(4):355-63. doi: 10.1007/s00115-002-1283-6.

Abstract

In contrast to the amnestic syndrome, unilateral hemispheric lesions are mostly connected with selective memory deficits, which are related to either verbal or visual-spatial information. Clinical studies concerning this are mostly about patients with temporal lobe epilepsy. Almost all studies found that significantly worse verbal memory deficits appeared before or after left temporal lobectomy. In contrast to these outcomes, the results concerning right temporal lobectomy (RTL) are nonuniform. There are studies that cannot prove figurative memory deficits before or after RTL and others that ascertain a correlation between RTL and figurative memory deficits. Mean values are always compared with random samples of left and right hemispheric patients. In contrast, the presented study assumes a clinical isolated case and analyses a random sample of neurological patients with different genesis with a standardized memory test (Berlin Amnesia Test, or BAT). As a result, a significant correlation between left hemispheric lesions and verbal memory deficits as well as right hemispheric lesions and visual-spatial memory deficits can be proven. Possible reasons for these differing results with visual-spatial memory deficits are still under discussion.

摘要

与遗忘综合征不同,单侧半球病变大多与选择性记忆缺陷有关,这些缺陷与言语或视觉空间信息相关。关于这方面的临床研究大多针对颞叶癫痫患者。几乎所有研究都发现,左颞叶切除术前或术后出现明显更严重的言语记忆缺陷。与这些结果相反,关于右颞叶切除术(RTL)的结果并不一致。有些研究无法证明RTL术前或术后存在形象记忆缺陷,而其他研究则确定了RTL与形象记忆缺陷之间的相关性。平均值总是与左右半球患者的随机样本进行比较。相比之下,本研究以一个临床孤立病例为假设,并用标准化记忆测试(柏林遗忘测试,或BAT)分析了不同病因的神经科患者随机样本。结果表明,左半球病变与言语记忆缺陷以及右半球病变与视觉空间记忆缺陷之间存在显著相关性。视觉空间记忆缺陷出现这些不同结果的可能原因仍在讨论中。

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