Ładny J R, Serwatka W, Polaków J
Centralna i Chirurgiczna Izba Przyjeć SPSK Akademii Medycznej w Białymstoku.
Przegl Lek. 2001;58(12):1079-82.
Acute pancreatitis is a potentially lethal disease and mortality depends on severity. The clinical spectrum of acute pancreatitis depends greatly on whether or not pancreatic necrosis is present and to what extend. The effectiveness of any treatment is related to the ability to early predict severity, but there is still no ideal predictive system or biochemical marker. An early enthusiasm over several biochemical markers has diminished because of the costs and impracticability of routine use. Undoubtedly, inflammatory mediators do appear capable of offering greater accuracy, speed and flexibility than older systems but they still require more improvement. Nowadays, prediction of acute pancreatitis severity is based on compilation of methods--clinical assessment, use of multifactor score system, measurement of biochemical markers and computed tomography.
急性胰腺炎是一种具有潜在致命性的疾病，死亡率取决于疾病的严重程度。急性胰腺炎的临床谱很大程度上取决于胰腺坏死是否存在以及坏死的程度。任何治疗的有效性都与早期预测严重程度的能力相关，但目前仍没有理想的预测系统或生化标志物。由于常规使用的成本和不实用性，对几种生化标志物早期的热情已经消退。毫无疑问，炎症介质似乎比以往的系统更能提供更高的准确性、速度和灵活性，但它们仍需要进一步改进。如今，急性胰腺炎严重程度的预测是基于多种方法的综合——临床评估、多因素评分系统的使用、生化标志物的检测以及计算机断层扫描。
