环磷酰胺治疗的大鼠实验性过敏性甲状腺炎的逆转
Reversal of experimental allergic thyroiditis in cyclophosphamide-treated rats.
作者信息
Paterson P Y, Drobish D G
出版信息
Clin Exp Immunol. 1975 Apr;20(1):125-9.
Abstract
A 10-day course of cyclophosphamide completely reversed the histopathological manifestations of experimental allergic thyroiditis in Wistar rats. This therapeutic effect of cyclophosphamide was sustained, no recrudescence of thyroid inflammation being detected among rats examined 4 weeks after immunosuppressive therapy.
摘要
为期10天的环磷酰胺疗程完全逆转了Wistar大鼠实验性过敏性甲状腺炎的组织病理学表现。环磷酰胺的这种治疗效果是持久的，在免疫抑制治疗4周后检查的大鼠中未检测到甲状腺炎症复发。
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引用本文的文献
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Autoimmune thyroiditis: conversion of low-responder mice to high-responders by cyclophosphamide.自身免疫性甲状腺炎：环磷酰胺将低反应小鼠转化为高反应小鼠。
Clin Exp Immunol. 1982 Mar;47(3):683-8.
本文引用的文献
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Studies on organ specificity. IV. Production of rabbit thyroid antibodies in the rabbit.器官特异性研究。IV. 家兔体内兔甲状腺抗体的产生
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