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[社区获得性肺炎。智利8例由嗜肺军团菌血清1型引起的重症肺炎报告]

[Community acquired pneumonia. Report of 8 cases of severe pneumonia by serogroup 1 Legionella pneumophila in Chile].

作者信息

Cabello Hernán, Cortés Claudia, Ruiz Mauricio, Jover Eli, Rivera Felipe, Segovia Erico, Luppi Mario, Concha Andrés, Descalzi Fernando, Cornejo Rodrigo

机构信息

Sección de Enfermedades Respiratorias, Hospital Clínico Universidad de Chile, Santos Dumontt 999.

出版信息

Rev Med Chil. 2002 Mar;130(3):309-13.

Abstract

Legionella pneumophila is the second cause of severe community acquired pneumonia. In Chile, however, there are few reports of pneumonia caused by Legionella. We report eight patients (6 men, aged 42 to 72 years old) with community-acquired pneumonia caused by Legionella pneumophila serogroup 1, confirmed by the measurement of urinary antigen. Clinical presentation was characterized by fever or hypothermia (in one case), cough, dyspnea and neurological abnormalities in four patients. Cigarette smoking was the most frequently identified risk factor. All patients had at least one American Thoracic Society severity criteria. Complications observed were acute hypoxemic respiratory failure in seven patients, shock in four, renal failure in four and need for mechanical ventilation in three. No patient died.

摘要

嗜肺军团菌是社区获得性重症肺炎的第二大病因。然而,在智利,由军团菌引起的肺炎报告较少。我们报告了8例(6名男性,年龄在42至72岁之间)由嗜肺军团菌血清1型引起的社区获得性肺炎患者,通过检测尿抗原得以确诊。临床表现的特征为发热或体温过低(1例)、咳嗽、呼吸困难,4例患者有神经学异常。吸烟是最常见的危险因素。所有患者至少符合一项美国胸科学会的严重程度标准。观察到的并发症包括7例急性低氧性呼吸衰竭、4例休克、4例肾衰竭以及3例需要机械通气。无患者死亡。

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