Yeo Hosup, Choi Young Hae, Kim Jinwoong
College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Korea.
Chem Pharm Bull (Tokyo). 2002 Jun;50(6):847-9. doi: 10.1248/cpb.50.847.
Two new pregnane glycosides, cynascyrosides D and E, were isolated from the roots of Cynanchum ascyrifolium. The structures of these compounds were determined on the basis of spectroscopic and chemical evidence as cynajapogenin A 3-O-alpha-L-cymaropyranosyl-(1-->4)-beta-D-digitoxopyranosyl-(1-->4)-beta-L-cymaropyranoside and cynajapogenin A 3-O-beta-D-glucopyranosyl-(1-->4)-alpha-L-diginopyranosyl-(1-->4)-beta-L-cymaropyranosyl-(1-->4)-beta-D-digitoxopyranoside.
从白首乌（Cynanchum ascyrifolium）根部分离得到两种新的孕甾糖苷，即白首乌苷D和白首乌苷E。基于光谱和化学证据，确定这些化合物的结构分别为cynajapogenin A 3 - O -α - L - 洋地黄糖基 -（1→4）-β - D - 地高辛糖基 -（1→4）-β - L - 洋地黄糖基苷和cynajapogenin A 3 - O -β - D - 葡萄糖基 -（1→4）-α - L - 洋地黄毒糖基 -（1→4）-β - L - 洋地黄糖基 -（1→4）-β - D - 地高辛糖基苷。
