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[多发性硬化病程中的疼痛]

[Pain in the course of multiple sclerosis].

作者信息

Fryze Waldemar, Zaborski Jacek, Członkowska Anna

机构信息

Oddziału Neurologicznego Specjalistycznego Psychiatryczno-Neurologicznego Zespołu Opieki Zdrowotnej w Gdańsku.

出版信息

Neurol Neurochir Pol. 2002 Mar-Apr;36(2):275-84.

Abstract

According to previous studies pain symptoms were a problem in multiple sclerosis (MS) patients. This is an important issue since symptom control, especially pain, assume high priorities in MS. The aim of study was to assess the incidence and type of pain symptoms in MS. In the study 104 consecutive patients with clinically definite MS, according to Posers criteria, were evaluated by questionnaire. In all patients brain MRI strongly suggested MS. 76% of patients had relapsing-remitting (RR) course of the disease. At any stage of the disease pain syndromes occurred in 70.2% of MS patients. In 8% patients pain was the first symptom of MS. The most common acute pain syndromes were: Lhermitte sign (26%) and painful tonic spasm (19%). The incidence of migraine was 8% and 26% had tension headache. Chronic pain occurred in 60% of MS patients. Most common were dysaesthetic extremity pain (45%), low back pain (34%) and painful leg spasm (22%). There was no correlation with age, sex, and duration of disease. Pain symptoms were more frequent in MS patients with higher EDSS score and spinal cord involvement. Pain syndromes are common in MS patients. There was no correlation with age, sex, and duration of the disease. Pain occurred more frequent in MS patients with higher EDSS score and in patients with spinal cord involvement.

摘要

根据以往研究,疼痛症状是多发性硬化症(MS)患者面临的一个问题。这是一个重要问题,因为症状控制,尤其是疼痛控制,在MS中具有高度优先性。本研究的目的是评估MS患者疼痛症状的发生率和类型。在该研究中,根据波泽斯标准,对104例连续的临床确诊MS患者进行了问卷调查。所有患者的脑部MRI均强烈提示为MS。76%的患者疾病病程为复发缓解型(RR)。在疾病的任何阶段,70.2%的MS患者出现疼痛综合征。8%的患者疼痛是MS的首发症状。最常见的急性疼痛综合征为:莱尔米特征(26%)和痛性强直性痉挛(19%)。偏头痛的发生率为8%,26%的患者有紧张性头痛。60%的MS患者出现慢性疼痛。最常见的是感觉异常性肢体疼痛(45%)、腰痛(34%)和腿部痛性痉挛(22%)。疼痛症状与年龄、性别和病程无关。EDSS评分较高且有脊髓受累的MS患者疼痛症状更频繁。疼痛综合征在MS患者中很常见。疼痛与年龄、性别和病程无关。EDSS评分较高的MS患者以及有脊髓受累的患者疼痛出现得更频繁。

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