• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[多发性硬化症中的疼痛——一个仍被低估的问题。多发性硬化症住院患者疼痛综合征的1年患病率、意义及护理质量]

[Pain in multiple sclerosis--a still underestimated problem. The 1 year prevalence of pain syndromes, significance and quality of care of multiple sclerosis inpatients].

作者信息

Pöllmann W, Feneberg W, Erasmus L-P

机构信息

Marianne-Strauss-Klinik, Berg.

出版信息

Nervenarzt. 2004 Feb;75(2):135-40. doi: 10.1007/s00115-003-1656-5.

DOI:10.1007/s00115-003-1656-5
PMID:14770283
Abstract

We evaluated the 1-year prevalence of pain syndromes and quality of care among 157 consecutive multiple sclerosis (MS) inpatients (90 f, 67 m) aged 19-85 years, with extended disability status scores of 1.0-8.5 and clinically definite MS. In a standardized questionnaire, only severe pain (pain intensity on visual analog scale of at least 4/10) was documented and classified which had occurred more often than three times or lasted longer than 1 week within the last year. Of 157 patients, 61% reported 176 pain syndromes: most frequent were headaches (40%), dysesthetic limb pain (19%), back pain (17%), and painful spasms (11%). Twelve percent of the pain syndromes were classified as worst symptom of MS, and in 68% insufficient care by the physicians consulted was reported. This was even true for the most frequent pain, migraine, in which clear treatment recommendations exist. There is thus an urgent need for physicians to keep this problem in mind when treating MS patients.

摘要

我们评估了157例年龄在19 - 85岁之间、扩展残疾状态评分在1.0 - 8.5且临床确诊为多发性硬化症(MS)的连续住院患者(90名女性,67名男性)的疼痛综合征1年患病率及护理质量。在一份标准化问卷中,仅记录并分类了严重疼痛(视觉模拟量表上疼痛强度至少为4/10),即在过去一年中出现次数超过三次或持续时间超过1周的疼痛。在157例患者中,61%报告了176种疼痛综合征:最常见的是头痛(40%)、感觉异常性肢体疼痛(19%)、背痛(17%)和疼痛性痉挛(11%)。12%的疼痛综合征被归类为MS最严重的症状,68%的患者报告所咨询的医生护理不足。对于最常见的疼痛——偏头痛而言亦是如此,尽管针对偏头痛存在明确的治疗建议。因此,医生在治疗MS患者时迫切需要牢记这一问题。

相似文献

1
[Pain in multiple sclerosis--a still underestimated problem. The 1 year prevalence of pain syndromes, significance and quality of care of multiple sclerosis inpatients].[多发性硬化症中的疼痛——一个仍被低估的问题。多发性硬化症住院患者疼痛综合征的1年患病率、意义及护理质量]
Nervenarzt. 2004 Feb;75(2):135-40. doi: 10.1007/s00115-003-1656-5.
2
Lifetime and actual prevalence of pain and headache in multiple sclerosis.多发性硬化症中疼痛和头痛的终生患病率及实际患病率。
Mult Scler. 2008 May;14(4):514-21. doi: 10.1177/1352458507085551.
3
Prevalence and natural history of pain in adults with multiple sclerosis: systematic review and meta-analysis.多发性硬化症成人疼痛的患病率和自然病程:系统评价和荟萃分析。
Pain. 2013 May;154(5):632-642. doi: 10.1016/j.pain.2012.12.002. Epub 2012 Dec 14.
4
[Pain in the course of multiple sclerosis].[多发性硬化病程中的疼痛]
Neurol Neurochir Pol. 2002 Mar-Apr;36(2):275-84.
5
The prevalence of pain in multiple sclerosis: a multicenter cross-sectional study.多发性硬化症中疼痛的患病率:一项多中心横断面研究。
Neurology. 2004 Sep 14;63(5):919-21. doi: 10.1212/01.wnl.0000137047.85868.d6.
6
Pain syndromes in multiple sclerosis patients - patient experience at Lipik Special Hospital for Medical Rehabilitation.
Acta Clin Croat. 2014 Dec;53(4):405-10.
7
Pain and sensory complaints in multiple sclerosis.多发性硬化症中的疼痛与感觉异常
Eur J Neurol. 2004 Jul;11(7):479-82. doi: 10.1111/j.1468-1331.2004.00815.x.
8
[Pain in multiple sclerosis. Clinical aspects and therapy].[多发性硬化症中的疼痛。临床方面与治疗]
Schweiz Med Wochenschr. 1990 Dec 29;120(51-52):1959-64.
9
Migraine headaches and pain with neuropathic characteristics: comorbid conditions in patients with multiple sclerosis.偏头痛和具有神经病理性特征的疼痛:多发性硬化症患者的共病情况。
Pain. 2013 Dec;154(12):2691-2699. doi: 10.1016/j.pain.2013.07.050. Epub 2013 Aug 2.
10
Chronic and acute pain syndromes in patients with multiple sclerosis.
Acta Neurol (Napoli). 1994 Jun;16(3):97-102.

引用本文的文献

1
Headache in multiple sclerosis and autoimmune disorders.多发性硬化症和自身免疫性疾病中的头痛
Neurol Sci. 2015 May;36 Suppl 1:75-8. doi: 10.1007/s10072-015-2146-9.
2
[Importance and treatment of spasticity in multiple sclerosis : results of the MOVE 1 study].[多发性硬化症中痉挛的重要性及治疗:MOVE 1研究结果]
Nervenarzt. 2013 Feb;84(2):214-22. doi: 10.1007/s00115-012-3724-1.
3
Pain in experimental autoimmune encephalitis: a comparative study between different mouse models.实验性自身免疫性脑脊髓炎中的疼痛:不同小鼠模型间的比较研究。

本文引用的文献

1
One-year prevalence of migraine in Austria: a nation-wide survey.奥地利偏头痛的一年患病率:一项全国性调查。
Cephalalgia. 2003 May;23(4):280-6. doi: 10.1046/j.1468-2982.2003.00509.x.
2
Interferon beta but not glatiramer acetate therapy aggravates headaches in MS.干扰素β而非醋酸格拉替雷治疗会加重多发性硬化症患者的头痛。
Neurology. 2002 Aug 27;59(4):636-9. doi: 10.1212/wnl.59.4.636.
3
[Pain in the course of multiple sclerosis].[多发性硬化病程中的疼痛]
J Neuroinflammation. 2012 Oct 6;9:233. doi: 10.1186/1742-2094-9-233.
4
Headache and multiple sclerosis: clinical and therapeutic correlations.头痛与多发性硬化症:临床与治疗的相关性
Neurol Sci. 2009 May;30 Suppl 1:S23-6. doi: 10.1007/s10072-009-0053-7.
5
Current management of pain associated with multiple sclerosis.多发性硬化症相关疼痛的当前管理方法。
CNS Drugs. 2008;22(4):291-324. doi: 10.2165/00023210-200822040-00003.
Neurol Neurochir Pol. 2002 Mar-Apr;36(2):275-84.
4
Sensory symptoms of multiple sclerosis: a hidden reservoir of morbidity.多发性硬化症的感觉症状:发病率的一个隐藏来源。
Mult Scler. 1999 Jun;5(3):179-83. doi: 10.1177/135245859900500307.
5
Acute and chronic pain syndromes in multiple sclerosis. A 5-year follow-up study.多发性硬化症中的急性和慢性疼痛综合征。一项为期5年的随访研究。
Ital J Neurol Sci. 1995 Dec;16(9):629-32. doi: 10.1007/BF02230913.
6
Headache caused by a single lesion of multiple sclerosis in the periaqueductal gray area.导水管周围灰质区多发性硬化单一病灶引起的头痛
Headache. 1993 Sep;33(8):452-5. doi: 10.1111/j.1526-4610.1993.hed3308452.x.
7
The co-occurrence of multiple sclerosis and migraine headache: the serotoninergic link.
Int J Neurosci. 1994 Jun;76(3-4):249-57. doi: 10.3109/00207459408986007.
8
Epidemiology of headache.头痛的流行病学
Cephalalgia. 1995 Feb;15(1):45-68. doi: 10.1046/j.1468-2982.1995.1501045.x.
9
Brain stem activation in spontaneous human migraine attacks.自发性人类偏头痛发作时的脑干激活
Nat Med. 1995 Jul;1(7):658-60. doi: 10.1038/nm0795-658.
10
New diagnostic criteria for multiple sclerosis: guidelines for research protocols.多发性硬化症的新诊断标准:研究方案指南。
Ann Neurol. 1983 Mar;13(3):227-31. doi: 10.1002/ana.410130302.