制备抗鹅膏毒素抗体作为其放射免疫测定的基础。
Production of antibodies to amanitins as the basis for their radioimmunoassay.
作者信息
Fiume L, Busi C, Campadelli-Fiume G, Franceschi C
出版信息
Experientia. 1975 Oct 15;31(10):1233-4. doi: 10.1007/BF02326810.
PMID:1204754
Abstract
The production of antibodies against amanitins is described. By means of these antibodies, a radioimmunoassay was developed which allows detection of as little as 0.5 ng of amanitins in 1 ml of serum. By this method, the clearance of alpha-amanitin from the blood of poisoned mice was measured.
摘要
描述了抗鹅膏毒肽抗体的产生。借助这些抗体，开发了一种放射免疫测定法，该方法能够检测出1毫升血清中低至0.5纳克的鹅膏毒肽。通过这种方法，测定了中毒小鼠血液中α-鹅膏毒肽的清除率。
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