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给予2,3,7,8-四氯二苯并对二恶英的小鼠肝脏中的病理变化。

Pathological changes in the liver of mice given 2,3,7,8-tetrachlorodibenzo-p-dioxin.

作者信息

Jones G, Greig J B

出版信息

Experientia. 1975 Nov 15;31(11):1315-7. doi: 10.1007/BF01945801.

DOI:10.1007/BF01945801
PMID:1204787
Abstract

In C57BL/6 mice a single oral dose of 2,3,7,8-tetrachlorodibenzodioxin (LD50 126 mug/kg) results in loss of body weight and death with an enlarged fatty liver after ca. 21 days. A progressive necrotic centrilobular liver lesion is also seen.

摘要

在C57BL/6小鼠中，单次口服剂量的2,3,7,8-四氯二苯并二恶英（半数致死量为126微克/千克）会导致体重减轻和死亡，约21天后会出现脂肪肝肿大。还可见进行性坏死性小叶中心性肝损伤。

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POSSIBLE SYNTHESIS OF POLYRIBONUCLEOTIDES OF KNOWN BASE-TRIPLET SEQUENCES.已知碱基三联体序列的多核糖核苷酸的可能合成
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