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Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on drug metabolism and hepatic microsomes of rats and mice.

作者信息

Greig J B, De Matteis F

出版信息

Environ Health Perspect. 1973 Sep;5:211-9. doi: 10.1289/ehp.7305211.

DOI:10.1289/ehp.7305211
PMID:4752904
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1474983/
Abstract
摘要

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1
Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on drug metabolism and hepatic microsomes of rats and mice.2,3,7,8-四氯二苯并对二恶英对大鼠和小鼠药物代谢及肝微粒体的影响。
Environ Health Perspect. 1973 Sep;5:211-9. doi: 10.1289/ehp.7305211.
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Effect of dibromotetrafluoroethane inhalation on hepatic drug metabolism in mice.
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3
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4
Comparison of 2,3,7,8-tetrachlorodibenzo-p-dioxin, a potent inducer of aryl hydrocarbon hydroxylase, with 3-methylcholanthrene.芳烃羟化酶的强效诱导剂2,3,7,8-四氯二苯并对二恶英与3-甲基胆蒽的比较。
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Cadmium inhibition of hepatic drug metabolism in the rat.镉对大鼠肝脏药物代谢的抑制作用。
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Stereoselective hydroxylation of hexobarbital enantiomers by rat liver microsomes.
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Mechanisms in the potentiation and inhibition of pharmacological actions of hexobarbital and zoxazolamine by glycofurol.聚乙二醇400对己巴比妥和唑恶唑胺药理作用的增强及抑制机制
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Effect of hexachlorobenzene on hepatic microsomal enzymes in the rat.
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Microsomal mixed-function oxidase activity and senescence-I. Hexobarbital sleep time and induction of components of the hepatic microsomal enzyme system in rats of different ages.
Exp Gerontol. 1975 Apr;10(2):89-99. doi: 10.1016/0531-5565(75)90039-x.

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Arch Toxicol. 1980 Oct;45(4):273-85. doi: 10.1007/BF00293808.
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Long-term hazards of polychlorinated dibenzodioxins and polychlorinated dibenzofurans.多氯二苯并二恶英和多氯二苯并呋喃的长期危害。
Environ Health Perspect. 1980 Jun;36:221-40. doi: 10.1289/ehp.8036221.
3
Urinary D-glucaric acid excretion in the Seveso area, polluted by tetrachloro-dibenzo-p-dioxin (TCDD): five years of experience.在受四氯二苯并对二恶英（TCDD）污染的塞韦索地区，尿中D-葡糖二酸排泄情况：五年经验
Environ Health Perspect. 1985 May;60:151-7. doi: 10.1289/ehp.60-1568553.
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Mechanism of action of toxic halogenated aromatics.有毒卤代芳烃的作用机制。
Environ Health Perspect. 1985 Feb;59:121-8. doi: 10.1289/ehp.59-1568090.
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The Ah receptor and the mechanism of dioxin toxicity.芳烃受体与二噁英毒性机制
Biochem J. 1991 Jun 1;276 ( Pt 2)(Pt 2):273-87. doi: 10.1042/bj2760273.
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Pathological changes in the liver of mice given 2,3,7,8-tetrachlorodibenzo-p-dioxin.给予2,3,7,8-四氯二苯并对二恶英的小鼠肝脏中的病理变化。
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Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the in vivo and in vitro dechlorination of pentachlorophenol.2,3,7,8-四氯二苯并对二噁英对五氯苯酚体内外脱氯的影响。
Arch Toxicol. 1978 Feb 21;40(1):55-61. doi: 10.1007/BF00353279.
8
Vitamin A (retinol) status in the rat after a single oral dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin.单次口服2,3,7,8-四氯二苯并对二噁英后大鼠体内的维生素A（视黄醇）状态
Arch Toxicol. 1979 Sep;42(4):265-74. doi: 10.1007/BF00334840.
9
Effects of 3,3',4,4'-tetrachloroazobenzene and 3,3',4,4'-tetrachloroazoxybenzene on rat liver microsomes.3,3',4,4'-四氯偶氮苯和3,3',4,4'-四氯氧化偶氮苯对大鼠肝脏微粒体的影响。
Bull Environ Contam Toxicol. 1979 Jul;22(4-5):638-42. doi: 10.1007/BF02027000.

本文引用的文献

1
Studies on the induction of CO-binding pigments in liver microsomes by phenobarbital and 3-methylcholanthrene.苯巴比妥和3-甲基胆蒽对肝微粒体中一氧化碳结合色素诱导作用的研究。
Biochem Biophys Res Commun. 1967 Nov 30;29(4):521-6. doi: 10.1016/0006-291x(67)90515-3.
2
Factors influencing induction of hepatic microsomal drug-metabolizing enzymes.影响肝微粒体药物代谢酶诱导的因素。
Biochem Pharmacol. 1962 Mar;11:211-20. doi: 10.1016/0006-2952(62)90076-x.
3
ETHIONINE CARCINOGENESIS.乙硫氨酸致癌作用
Adv Cancer Res. 1963;7:383-474. doi: 10.1016/s0065-230x(08)60986-0.
4
Fractional solubilization of haemoproteins and partial purification of carbon monoxide-binding cytochrome from liver microsomes.血红蛋白的分级溶解及从肝微粒体中部分纯化一氧化碳结合细胞色素
Biochim Biophys Acta. 1963 Apr 2;71:224-6. doi: 10.1016/0006-3002(63)91015-1.
5
Adenosine triphosphatase in the microsomal fraction from rat brain.大鼠脑微粒体部分中的三磷酸腺苷酶
Biochem J. 1962 Jun;83(3):527-33. doi: 10.1042/bj0830527.
6
The metabolic fate of zoxazolamine (flexin) in man.唑氯胺（肌柔）在人体中的代谢转归
J Pharmacol Exp Ther. 1960 Apr;128:333-9.
7
Adaptive increases in drug-metabolizing enzymes induced by phenobarbital and other drugs.苯巴比妥及其他药物诱导的药物代谢酶适应性增加。
J Pharmacol Exp Ther. 1960 Sep;130:1-8.
8
Zoxazolamine: physiological disposition, uricosuric properties.唑沙宗：生理处置、促尿酸排泄特性。
Am J Med. 1958 Sep;25(3):401-8. doi: 10.1016/0002-9343(58)90079-2.
9
The metabolism of methylated aminoazo dyes. V. Evidence for induction of enzyme synthesis in the rat by 3-methylcholanthrene.甲基化氨基偶氮染料的代谢。V. 3-甲基胆蒽诱导大鼠酶合成的证据。
Cancer Res. 1956 Jun;16(5):450-9.
10
The enzymatic metabolism of hexobarbital (evipal).己巴比妥（佛罗那）的酶促代谢
J Pharmacol Exp Ther. 1955 Aug;114(4):409-17.