四氧嘧啶糖尿病大鼠电休克惊厥阈值的变化
Changes of electro-shock seizure threshold in alloxan diabetic rats.
作者信息
Koltai M, Minker E
出版信息
Experientia. 1975 Nov 15;31(11):1369. doi: 10.1007/BF01945833.
PMID:1204807
Abstract
During a 4-week period, the electroshock seizure threshold (EST) of R Amsterdam rats was determined. When alloxan induced diabetes, the EST values significantly decreased, while in the alloxan-treated non-diabetic group they remained unchanged. The results suggest that diabetes induces increased excitability in the central nervous system.
摘要
在为期4周的时间里，测定了R阿姆斯特丹大鼠的电休克惊厥阈值（EST）。当用四氧嘧啶诱导糖尿病时，EST值显著降低，而在四氧嘧啶处理的非糖尿病组中，EST值保持不变。结果表明，糖尿病会导致中枢神经系统兴奋性增加。
Zotero 插件