Narendranath R, Kiracofe G H
Indian J Physiol Pharmacol. 1975 Jul-Sep;19(3):140-5.
High ambient temperature (34.4 C degrees and 60-65% relative humidity (RH failed to maintain optimum embryonic and/or foetal survival rate in ovariectomized pregnant rats given exogenous progesterone and oestrone injections. A still higher ambient environment (36.6 C degrees and 70-75% RH) did not affect the decidual cell response (DCR) in psuedo-pregnant rats. Heat stress did not result either in insufficiency or lack of progesterone and hence the latter two are not factors for the heat stress causing embryonic and/or foetal loss. The possibility of the failure of oestrone being converted to oestradiol or an intrinsic interference of RNA synthesis to be the factors responsible for embryonic and/or foetal loss caused by heat stress has been examined.
在对切除卵巢的怀孕大鼠注射外源性孕酮和雌酮的情况下,高环境温度(34.4摄氏度,相对湿度60 - 65%)未能维持最佳的胚胎和/或胎儿存活率。更高的环境温度(36.6摄氏度,相对湿度70 - 75%)并未影响假孕大鼠的蜕膜细胞反应(DCR)。热应激并未导致孕酮不足或缺乏,因此后两者并非热应激导致胚胎和/或胎儿损失的因素。已经研究了雌酮未能转化为雌二醇或RNA合成的内在干扰成为热应激导致胚胎和/或胎儿损失的因素的可能性。