Harvey S D, Nelson D A, Wright B W, Grate J W
Pacific Northwest National Laboratory, Richland, WA 99352, USA.
J Chromatogr A. 2002 Apr 19;954(1-2):217-25. doi: 10.1016/s0021-9673(02)00188-7.
A number of critical field applications require monitoring air samples for trace levels of chemical warfare agents. Solid-phase microextraction (SPME) is a convenient format to conduct these analyses. Measurements could be significantly improved if a SPME phase selective for nerve agents were substituted for non-selective polymers typically used (e.g., polydimethylsiloxane). This paper evaluates a novel stationary phase, previously developed for methylphosphonate sensor applications, for use with SPME sampling. The phenol-based polymer, BSP3, was found to offer far higher selectivity toward sarin (GB) than polydimethylsiloxane due to a pronounced affinity toward the target analyte and a lower affinity toward hydrocarbons.
许多关键的现场应用需要监测空气样本中的痕量化学战剂。固相微萃取（SPME）是进行这些分析的一种便捷方式。如果用对神经毒剂具有选择性的SPME固定相替代通常使用的非选择性聚合物（如聚二甲基硅氧烷），测量结果可能会得到显著改善。本文评估了一种先前为甲基膦酸酯传感器应用而开发的新型固定相，用于SPME采样。基于苯酚的聚合物BSP3被发现对沙林（GB）的选择性远高于聚二甲基硅氧烷，这是由于对目标分析物有明显的亲和力，而对碳氢化合物的亲和力较低。
