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在经皮肝穿刺治疗复杂右肝内胆管结石伴肝内胆管狭窄方面,改良手术是否明显优于传统手术?

Are modified procedures significantly better than conventional procedures in percutaneous transhepatic treatment for complicated right hepatolithiasis with intrahepatic biliary strictures?

作者信息

Jeng K S, Sheen I S, Yang F S

机构信息

Dept of Surgery and Radiology, Mackay Memorial Hospital, Taipei, Taiwan, Republic of China.

出版信息

Scand J Gastroenterol. 2002 May;37(5):597-601. doi: 10.1080/00365520252903161.

DOI:10.1080/00365520252903161
PMID:12059063
Abstract

BACKGROUND

Conventional percutaneous procedures for treating patients with recurrent hepatolithiasis associated with complicated intrahepatic biliary strictures require multiple dilation sessions before stone extraction. We modified the approach, reducing the number of dilation sessions required and using newer lithotripsy and irrigation methods. We suggest that the modified procedures are superior to conventional management and demonstrate their utility in clearing hepatolithiasis.

METHODS

Percutaneous transhepatic stricture dilation and cholangioscopic lithotripsy were performed to treat patients with right recurrent hepatolithiasis with complicated intrahepatic biliary strictures. Conventional methods were used in 40 patients (Group A). Modified methods, including simplification of tract establishment and stricture dilation and electrohydraulic lithotripsy (EHL) were used in 60 patients (Group B).

RESULTS

Group B patients had fewer complications (massive hemobilia: 0% versus 15%, P = 0.0032, cholangitis: 0% versus 17.5%, P=0.0012), tolerated the procedures better (intolerable pain: 0% versus 12.5%, P=0.0087), had a higher rate of success (residual stones: 3.3% versus 20%, P=0.0132; remaining asymptomatic and stone-free: 81% versus 50%, P = 0.0021), a shorter hospital stay (17.8 +/- 4.4 days versus 36.2 +/- 5.5 days, P < 0.001) and lower overall expense (USD 2689 versus USD 3848) than Group A patients.

CONCLUSION

We believe that the modified methods are superior to conventional treatment in that they effectively decrease procedural complications and cost, and significantly improve treatment results.

摘要

背景

对于患有复发性肝内胆管结石并伴有复杂肝内胆管狭窄的患者,传统的经皮治疗方法在取石前需要多次扩张。我们改进了方法,减少了所需的扩张次数,并采用了更新的碎石和冲洗方法。我们认为改进后的方法优于传统治疗方法,并证明了其在清除肝内胆管结石方面的效用。

方法

对患有右复发性肝内胆管结石并伴有复杂肝内胆管狭窄的患者进行经皮肝穿刺胆管狭窄扩张术和胆道镜碎石术。40例患者采用传统方法(A组)。60例患者采用改进方法,包括简化通道建立和狭窄扩张以及电液压碎石术(EHL)(B组)。

结果

B组患者并发症较少(大量胆血瘘:0%对15%,P = 0.0032;胆管炎:0%对17.5%,P = 0.0012),对手术的耐受性更好(难以忍受的疼痛:0%对12.5%,P = 0.0087),成功率更高(残余结石:3.3%对20%,P = 0.0132;保持无症状且无结石:81%对50%,P = 0.0021),住院时间更短(17.8±4.4天对36.2±5.5天,P < 0.001),总体费用更低(2689美元对3848美元)。

结论

我们认为改进后的方法优于传统治疗方法,因为它们能有效减少手术并发症和成本,并显著提高治疗效果。

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