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次优的麻疹-腮腺炎-风疹疫苗接种覆盖率促使爱尔兰发生了一起输入性麻疹疫情。

Suboptimal measles-mumps-rubella vaccination coverage facilitates an imported measles outbreak in ireland.

作者信息

Coughlan Suzie, Connell Jeff, Cohen Bernard, Jin Li, Hall William W

机构信息

National Virus Reference Laboratory, University College Dublin, Dublin 4, Ireland.

出版信息

Clin Infect Dis. 2002 Jul 1;35(1):84-6. doi: 10.1086/340708. Epub 2002 Jun 6.

DOI:10.1086/340708
PMID:12060880
Abstract

The year 2000 saw a dramatic increase in the incidence of measles infections in Ireland, with >1500 cases documented. Initial cases were reported from an area of Dublin with low vaccine uptake and a large immigrant population. Molecular epidemiologic findings revealed that the strain of measles virus responsible for this outbreak was the genotype D2 strain, which is closely related to strains initially identified in South Africa. It is suggested that suboptimal vaccine uptake facilitated the spread of imported measles infection.

摘要

2000年,爱尔兰麻疹感染发病率急剧上升,记录在案的病例超过1500例。最初的病例报告来自都柏林一个疫苗接种率低且移民人口众多的地区。分子流行病学研究结果显示,此次疫情的麻疹病毒株为D2基因型毒株,与最初在南非发现的毒株密切相关。据推测,疫苗接种率欠佳助长了输入性麻疹感染的传播。

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