Pike Jamison, Tippins Ashley, Nyaku Mawuli, Eckert Maribeth, Helgenberger Louisa, Underwood J Michael
Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Disease, Immunization Services Division, Atlanta, GA, United States.
Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Disease, Immunization Services Division, Atlanta, GA, United States.
Vaccine. 2017 Oct 13;35(43):5905-5911. doi: 10.1016/j.vaccine.2017.08.075. Epub 2017 Sep 5.
After 20years with no reported measles cases, on May 15, 2014 the Centers for Disease Control and Prevention (CDC) was notified of two cases testing positive for measles-specific immunoglobulin M (IgM) antibodies in the Federated States of Micronesia (FSM). Under the Compact of Free Association, FSM receives immunization funding and technical support from the United States (US) domestic vaccination program managed by the Centers for Disease Control and Prevention (CDC). In a collaborative effort, public health officials and volunteers from FSM and the US government worked to respond and contain the measles outbreak through an emergency mass vaccination campaign, contact tracing, and other outbreak investigation activities. Contributions were also made by United Nations Children's Emergency Fund (UNICEF) and World Health Organization (WHO). Total costs incurred as a result of the outbreak were nearly $4,000,000; approximately $10,000 per case. Direct medical costs (≈$141,000) were incurred in the treatment of those individuals infected, as well as lost productivity of the infected and informal caregivers (≈$250,000) and costs to contain the outbreak (≈$3.5 million). We assessed the economic burden of the 2014 measles outbreak to FSM, as well as the economic responsibilities of the US. Although the US paid the majority of total costs of the outbreak (≈67%), examining each country's costs relative to their respective economy illustrates a far greater burden to FSM. We demonstrate that while FSM was heavily assisted by the US in responding to the 2014 Measles Outbreak, the outbreak significantly impacted their economy. FSM's economic burden from the outbreak is approximately equivalent to their entire 2016 Fiscal Year budget dedicated to education.
在连续20年未报告麻疹病例之后,2014年5月15日,美国疾病控制与预防中心(CDC)接到通知,密克罗尼西亚联邦(FSM)有两例麻疹特异性免疫球蛋白M(IgM)抗体检测呈阳性的病例。根据《自由联合协定》,密克罗尼西亚联邦从由美国疾病控制与预防中心(CDC)管理的美国国内疫苗接种计划获得免疫接种资金和技术支持。在一项合作行动中,密克罗尼西亚联邦和美国政府的公共卫生官员及志愿者通过紧急大规模疫苗接种运动、接触者追踪及其他疫情调查活动,努力应对并控制麻疹疫情。联合国儿童基金会(UNICEF)和世界卫生组织(WHO)也做出了贡献。此次疫情造成的总成本接近400万美元;每例约10000美元。治疗受感染个体产生了直接医疗费用(约141000美元),以及受感染个体和非正式护理人员的生产力损失(约250000美元)和控制疫情的费用(约350万美元)。我们评估了2014年麻疹疫情给密克罗尼西亚联邦造成的经济负担以及美国的经济责任。尽管美国支付了疫情总成本的大部分(约67%),但相对于各自的经济状况来审视每个国家的成本,就会发现密克罗尼西亚联邦的负担要大得多。我们证明,虽然密克罗尼西亚联邦在应对2014年麻疹疫情时得到了美国的大力协助,但疫情仍对其经济产生了重大影响。此次疫情给密克罗尼西亚联邦造成的经济负担大约相当于其2016财年用于教育的全部预算。