Madar R, Straka S, Baska T
Institute of Epidemiology, Jessenius Faculty of Medicine, Comenius University, Bratislava, Slovakia.
Bratisl Lek Listy. 2002;103(1):38-41.
Saliva is a body fluid containing antibodies of diagnostic significance. Unlike venipuncture, saliva collection (by brushing the teeth and rubbing the gums) is painless, non-invasive, inexpensive, simple and rapid. By using sensitive immunoassays in salivary specimens it is possible to diagnose immunoglobulins against a wide range of infectious diseases e.g. hepatitis A, B and C, measles, mumps, rubella, human immunodeficiency virus, Epstein-Barr virus, parvovirus B 19, human herpesvirus 6 and Helicobacter pylori infections. Salivary antibody testing may provide better access to epidemic outbreaks, children, large populations, hard-to-reach risk groups and may thus play a major role in the surveillance and control of infectious diseases. (Tab. 2, Ref. 34.)
唾液是一种含有具有诊断意义抗体的体液。与静脉穿刺不同，唾液采集（通过刷牙和摩擦牙龈）无痛、无创、廉价、简单且快速。通过在唾液样本中使用灵敏的免疫测定法，有可能诊断出针对多种传染病的免疫球蛋白，例如甲型、乙型和丙型肝炎、麻疹、腮腺炎、风疹、人类免疫缺陷病毒、爱泼斯坦 - 巴尔病毒、细小病毒B19、人类疱疹病毒6以及幽门螺杆菌感染。唾液抗体检测可为疫情爆发地区、儿童、大量人群、难以接触到的风险群体提供更好的检测途径，因此可能在传染病监测和控制中发挥重要作用。（表2，参考文献34。）
