Fabre C, Signoret J P
C R Acad Hebd Seances Acad Sci D. 1978 May 29;286(21):1527-30.
Daily I/M injections of 200 microgram of oestradiol benzoate induce in female Sheep, ovariectomized as adults, male-like sexual reactions similar to what is obtained with 10 mg testosterone propionate per day. Simultaneously, a permanent female sexual receptivity is observed. Oestradiol benzoate at the dose of 20 microgram/day, and dihydrotestosterone propionate (10 mg/day) are both totally ineffective. The result support the hypothesis of the necessity of the aromatization of testosterone for the action on sexual behaviour.
每天对成年后进行卵巢切除的雌性绵羊进行200微克苯甲酸雌二醇的皮下注射或肌肉注射,会引发类似雄性的性行为反应,这与每天注射10毫克丙酸睾酮所产生的反应相似。同时,还观察到了永久性的雌性性接受能力。每天20微克剂量的苯甲酸雌二醇以及丙酸双氢睾酮(每天10毫克)均完全无效。这些结果支持了睾酮芳香化对于性行为作用的必要性这一假说。