Gross Allan E, Blackley Hugh, Wong Paul, Saleh Khal, Woodgate Ian
University of Toronto, Division of Orthopaedic Surgery, Mount Sinai Hospital, Toronto, Ontario, Canada.
Instr Course Lect. 2002;51:103-13.
The role of allograft tissue, including bone, cartilage and soft tissue, has become more defined in lower extremity reconstructive surgery. Revision arthroplasty of the hip commonly requires restoration of bone stock using allograft bone. Morcellized bone is used for contained defects on both the acetabular and femoral sides. Structural allograft bone is used for uncontained or segmental defects, and the results are less predictable; therefore, its use is more controversial. Alternatives include the jumbo cup, oblong cup, and high hip center on the pelvic side and tumor prostheses or distal fixation on the femoral side. These alternatives do not, however, restore bone stock, thus making further surgery more difficult. Structural grafts allow attachment of bone and soft tissue and restoration of the correct anatomy and have been shown to restore bone stock for further surgery, particularly on the acetabular side. Improvements in the quality and safety of banked bone and the development of surgical techniques have enhanced the results of structural allograft bone grafting. Restoring bone stock in revision arthroplasty of the hip is an accepted standard for the patient likely to undergo further surgery. Continuing to develop technologies that will facilitate the use of allograft tissue is imperative.
同种异体组织,包括骨、软骨和软组织,在下肢重建手术中的作用已变得更加明确。髋关节翻修置换术通常需要使用同种异体骨来恢复骨量。碎骨用于髋臼和股骨侧的局限性缺损。结构性同种异体骨用于非局限性或节段性缺损,但结果较难预测,因此其应用更具争议性。替代方法包括在骨盆侧使用大臼杯、椭圆形杯和高髋关节中心,以及在股骨侧使用肿瘤假体或远端固定。然而,这些替代方法并不能恢复骨量,从而使进一步手术更加困难。结构性移植可实现骨与软组织的附着以及正确解剖结构的恢复,并且已证明能为进一步手术恢复骨量,尤其是在髋臼侧。库存骨质量和安全性的提高以及手术技术的发展增强了结构性同种异体骨移植的效果。在髋关节翻修置换术中恢复骨量是可能接受进一步手术的患者的公认标准。继续开发有助于使用同种异体组织的技术势在必行。