Lin S K, Tin-Wa M, Taylor E H
J Pharm Sci. 1975 Dec;64(12):2021-2. doi: 10.1002/jps.2600641231.
Thirty actinomycetes were isolated from soil samples and screened for their ability to modify the structure of aspidospermine. One actinomycete culture converted aspidospermine into O-demethylaspidospermine but failed to modify N-deacetylaspidospermine, N-ethyl-N-deacetylaspidospermine, 7-methoxyindole, and 7-methoxytryptophan.
从土壤样本中分离出30株放线菌,并对其修饰阿朴菲宁结构的能力进行筛选。一种放线菌培养物将阿朴菲宁转化为O-去甲基阿朴菲宁,但未能修饰N-去乙酰阿朴菲宁、N-乙基-N-去乙酰阿朴菲宁、7-甲氧基吲哚和7-甲氧基色氨酸。