Xue Charlie Changli, English Robert, Zhang Jerry Jiansheng, Da Costa Cliff, Li Chun Guang
The Chinese Medicine Unit, RMIT University, Bundoora, Victoria, Australia.
Am J Chin Med. 2002;30(1):1-11. doi: 10.1142/S0192415X0200020X.
The clinical efficacy and safety of acupuncture in the treatment of Seasonal Allergic Rhinitis (SAR) was evaluated by employing a two-phase crossover single-blind clinical trial. Thirty subjects were randomly assigned to two groups with 17 and 13 subjects respectively and treated with real or sham acupuncture (three times per week) for four consecutive weeks and then a crossover for treatments for a further four weeks without a washout period. The administration of real acupuncture treatment was guided by a syndrome differentiation according to Chinese Medicine Theory. Subjects were assessed by various criteria before, during and after the treatments. Outcome measures included subjective symptom scores using a five-point scale (FPS), relief medication scores (RMS) and adverse effect records. Twenty-six (26) subjects completed the study. There was a significant improvement in FPS (nasal and non-nasal symptoms) between the two types of acupuncture treatments. No significant differences were shown in RMS between the real acupuncture treatment group and the sham acupuncture treatment group. No side effects were observed for both groups. The results indicate that acupuncture is an effective and safe alternative treatment for the management of SAR.
采用两阶段交叉单盲临床试验评估针刺治疗季节性变应性鼻炎(SAR)的临床疗效和安全性。30名受试者被随机分为两组,分别为17名和13名,接受真针刺或假针刺治疗(每周3次),连续4周,然后交叉治疗4周,无洗脱期。真针刺治疗根据中医理论辨证施治。在治疗前、治疗期间和治疗后,根据各种标准对受试者进行评估。观察指标包括采用五点量表(FPS)的主观症状评分、缓解药物评分(RMS)和不良反应记录。26名受试者完成了研究。两种针刺治疗之间的FPS(鼻部和非鼻部症状)有显著改善。真针刺治疗组和假针刺治疗组的RMS无显著差异。两组均未观察到副作用。结果表明,针刺是治疗SAR的一种有效且安全的替代疗法。