用于过敏性鼻炎的草药疗法（补中益气汤）：一项对照试验系统评价的方案
Herbal medicine (Bojungikki-tang) for allergic rhinitis: A protocol for a systematic review of controlled trials.
作者信息
Lee Ju Ah, Jang Soobin, Jun Ji Hee, Lee Myeong Soo, Lee Eunhee, Kim Namkwen, Lee Dong Hyo
机构信息
Department of Korean Internal Medicine, College of Korean Medicine, Gachon University, Gyeonggi-do KM Fundamental Research Division Clinical Research Division, Korea Institute of Oriental Medicine, Daejeon Department of Obstetrics and Gynecology, College of Korean Medicine, Woosuk University, Jeonju Department of Ophthalmology and Otolaryngology and Dermatology, School of Korean Medicine, Pusan National University, Yangsan Department of Ophthalmology, Otolaryngology and Dermatology, College of Korean Medicine, Woosuk University, Jeonju, Korea.
出版信息
Medicine (Baltimore). 2018 Jan;97(3):e9551. doi: 10.1097/MD.0000000000009551.
BACKGROUND
Bojungikki-tang, a herbal medicine for strengthening the digestive system, has been widely used in East Asian countries since the Yuan Dynasty in China. Moreover, Bojungikki-tang has reportedly exhibited anti-allergy effects in many clinical trials. This systematic review will assess the effectiveness and safety of Bojungikki-tang for allergic rhinitis (AR).
METHODS AND ANALYSIS
Eleven databases, including Asian databases, will be searched for studies conducted through October 2017. We will include randomized controlled trials (RCTs) assessing Bojungikki-tang for AR. The risk of bias will be evaluated using the Cochrane risk of bias assessment tool, and confidence in the cumulative evidence will be evaluated using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) instrument.
ETHICS AND DISSEMINATION
This systematic review will be published in a peer-reviewed journal and will also be disseminated electronically and in print. The review will be updated to inform and guide health care practices.
REGISTRATION
The protocol for this systematic review has been registered in PROSPERO (https://www.crd.york.ac.uk/PROSPERO) under number CRD42017068993.
背景
补中益气汤是一种用于增强消化系统功能的草药，自中国元朝以来在东亚国家广泛使用。此外，据报道，补中益气汤在许多临床试验中已显示出抗过敏作用。本系统评价将评估补中益气汤治疗变应性鼻炎（AR）的有效性和安全性。
方法与分析
将检索包括亚洲数据库在内的11个数据库，以查找截至2017年10月进行的研究。我们将纳入评估补中益气汤治疗AR的随机对照试验（RCT）。将使用Cochrane偏倚风险评估工具评估偏倚风险，并使用推荐分级评估、制定和评价（GRADE）工具评估对累积证据的置信度。
伦理与传播
本系统评价将发表在同行评审期刊上，也将以电子和印刷形式传播。该评价将进行更新，以为医疗保健实践提供信息和指导。
注册
本系统评价的方案已在国际前瞻性系统评价注册库（https://www.crd.york.ac.uk/PROSPERO）注册，注册号为CRD42017068993。
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