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Japanese guidelines for allergic rhinitis 2017.《2017年日本变应性鼻炎指南》
Allergol Int. 2017 Apr;66(2):205-219. doi: 10.1016/j.alit.2016.11.001. Epub 2017 Feb 15.
2
Effect of Inhalation of Aromatherapy Oil on Patients with Perennial Allergic Rhinitis: A Randomized Controlled Trial.吸入香薰油对常年性变应性鼻炎患者的影响：一项随机对照试验。
Evid Based Complement Alternat Med. 2016;2016:7896081. doi: 10.1155/2016/7896081. Epub 2016 Mar 13.
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Immune-modulatory effects of bu-zhong-yi-qi-tang in ovalbumin-induced murine model of allergic asthma.补中益气汤对卵清蛋白诱导的小鼠过敏性哮喘模型的免疫调节作用
PLoS One. 2015 Jun 2;10(6):e0127636. doi: 10.1371/journal.pone.0127636. eCollection 2015.
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Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation.系统评价和荟萃分析议定书的首选报告项目（PRISMA-P）2015：详细说明和解释。
BMJ. 2015 Jan 2;350:g7647. doi: 10.1136/bmj.g7647.
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Complementary and alternative therapy (CAM) in the treatment of allergic rhinitis.补充和替代疗法（CAM）治疗变应性鼻炎
Curr Allergy Asthma Rep. 2014 Dec;14(12):479. doi: 10.1007/s11882-014-0479-8.
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Bojungikki-tang for cancer-related fatigue: a pilot randomized clinical trial.补中益气汤治疗癌症相关性乏力：一项随机临床试验的初步研究。
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The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration.评估卫生保健干预措施的研究的系统评价和Meta分析报告的PRISMA声明：解释与详述。
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The diagnosis and management of rhinitis: an updated practice parameter.鼻炎的诊断与管理：一份更新的实践参数
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Antiinflammatory effects of Bu-zhong-yi-qi-tang in patients with perennial allergic rhinitis.补中益气汤对常年性变应性鼻炎患者的抗炎作用。
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A double-blind, randomized, placebo-controlled trial of acupuncture for the treatment of childhood persistent allergic rhinitis.一项关于针灸治疗儿童持续性变应性鼻炎的双盲、随机、安慰剂对照试验。
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用于过敏性鼻炎的草药疗法（补中益气汤）：一项对照试验系统评价的方案

Herbal medicine (Bojungikki-tang) for allergic rhinitis: A protocol for a systematic review of controlled trials.

作者信息

Lee Ju Ah, Jang Soobin, Jun Ji Hee, Lee Myeong Soo, Lee Eunhee, Kim Namkwen, Lee Dong Hyo

机构信息

Department of Korean Internal Medicine, College of Korean Medicine, Gachon University, Gyeonggi-do KM Fundamental Research Division Clinical Research Division, Korea Institute of Oriental Medicine, Daejeon Department of Obstetrics and Gynecology, College of Korean Medicine, Woosuk University, Jeonju Department of Ophthalmology and Otolaryngology and Dermatology, School of Korean Medicine, Pusan National University, Yangsan Department of Ophthalmology, Otolaryngology and Dermatology, College of Korean Medicine, Woosuk University, Jeonju, Korea.

出版信息

Medicine (Baltimore). 2018 Jan;97(3):e9551. doi: 10.1097/MD.0000000000009551.

DOI:10.1097/MD.0000000000009551
PMID:29504976
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5779745/
Abstract

BACKGROUND

Bojungikki-tang, a herbal medicine for strengthening the digestive system, has been widely used in East Asian countries since the Yuan Dynasty in China. Moreover, Bojungikki-tang has reportedly exhibited anti-allergy effects in many clinical trials. This systematic review will assess the effectiveness and safety of Bojungikki-tang for allergic rhinitis (AR).

METHODS AND ANALYSIS

Eleven databases, including Asian databases, will be searched for studies conducted through October 2017. We will include randomized controlled trials (RCTs) assessing Bojungikki-tang for AR. The risk of bias will be evaluated using the Cochrane risk of bias assessment tool, and confidence in the cumulative evidence will be evaluated using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) instrument.

ETHICS AND DISSEMINATION

This systematic review will be published in a peer-reviewed journal and will also be disseminated electronically and in print. The review will be updated to inform and guide health care practices.

REGISTRATION

The protocol for this systematic review has been registered in PROSPERO (https://www.crd.york.ac.uk/PROSPERO) under number CRD42017068993.

摘要

背景

补中益气汤是一种用于增强消化系统功能的草药，自中国元朝以来在东亚国家广泛使用。此外，据报道，补中益气汤在许多临床试验中已显示出抗过敏作用。本系统评价将评估补中益气汤治疗变应性鼻炎（AR）的有效性和安全性。

方法与分析

将检索包括亚洲数据库在内的11个数据库，以查找截至2017年10月进行的研究。我们将纳入评估补中益气汤治疗AR的随机对照试验（RCT）。将使用Cochrane偏倚风险评估工具评估偏倚风险，并使用推荐分级评估、制定和评价（GRADE）工具评估对累积证据的置信度。

伦理与传播

本系统评价将发表在同行评审期刊上，也将以电子和印刷形式传播。该评价将进行更新，以为医疗保健实践提供信息和指导。

注册

本系统评价的方案已在国际前瞻性系统评价注册库（https://www.crd.york.ac.uk/PROSPERO）注册，注册号为CRD42017068993。