Neimark Harold, Barnaud Antoine, Gounon Pierre, Michel Jean-Claude, Contamin Hugues
Department of Microbiology and Immunology, Morse Institute for Molecular Biology, Campus Box 44, College of Medicine, State University of New York, Brooklyn, NY 11203, USA.
Microbes Infect. 2002 Jun;4(7):693-8. doi: 10.1016/s1286-4579(02)01588-5.
Splenectomised squirrel monkeys (Saimiri sciureus) are increasingly being used as an experimental host for human malaria studies, notably for the assessment of candidate vaccines against Plasmodium falciparum blood-stage infection. Recently, S. sciureus monkeys in our primate-breeding colony were reported to be asymptomatic carriers of a putative Haemobartonella species. Patent haemobartonella infection is frequently activated following splenectomy, and may interfere with studies on the course of P. falciparum parasitaemia in these animals. Here, we show by 16S rRNA gene sequence analysis that this wall-less bacterium is not a rickettsia but, instead, is a haemotrophic mycoplasma. Haemotrophic mycoplasmas are a newly identified group of mycoplasmas that parasitise the surfaces of erythrocytes of a wide variety of vertebrate hosts.
脾切除的松鼠猴（松鼠猴属）越来越多地被用作人类疟疾研究的实验宿主，特别是用于评估针对恶性疟原虫血液阶段感染的候选疫苗。最近，据报道，我们灵长类动物繁殖群体中的松鼠猴是一种假定的血巴尔通体属物种的无症状携带者。脾切除术后，显性血巴尔通体感染经常被激活，这可能会干扰这些动物体内恶性疟原虫血症病程的研究。在这里，我们通过16S rRNA基因序列分析表明，这种无细胞壁细菌不是立克次氏体，而是一种血营养支原体。血营养支原体是一组新发现的支原体，它们寄生于多种脊椎动物宿主的红细胞表面。
