Hetzer R, Dragojevic D
Langenbecks Arch Chir. 1975;Suppl:427-9.
In 20 dogs one common iliac artery was intimectomized, an equal segment of the other was replaced by a knitted dacron prosthesis. Ten animals were given Acetylsalicylic Acid 30 mg/kg BW/d. Four weeks later these arterial segments were examined grossly and histologically for the presence of thrombotic depositis. In the treated animals these segments always remained patent. Three of the untreated animals showed a complete thrombotic occlusion of the prosthesis. The amount of thrombotic deposits on intimectomized and prosthetics segments was clearly reduced in the treated animals.
在20只狗身上，将一条髂总动脉进行内膜切除术，另一条相同长度的动脉段用针织涤纶假体替换。10只动物给予乙酰水杨酸，剂量为30毫克/千克体重/天。四周后，对这些动脉段进行大体和组织学检查，以确定是否存在血栓沉积。在接受治疗的动物中，这些动脉段始终保持通畅。三只未接受治疗的动物出现了假体完全血栓闭塞的情况。在接受治疗的动物中，内膜切除段和假体段上的血栓沉积量明显减少。
