Suppr超能文献

土耳其儿童年龄组甲型和戊型肝炎病毒抗体血清流行率

Seroprevalence of antibodies to hepatitis A and E viruses in pediatric age groups in Turkey.

作者信息

Colak D, Ogunc D, Gunseren F, Velipasaoglu S, Aktekin M R, Gültekin M

机构信息

Department of Clinical Microbiology, Akdeniz University Medical School, Antalya, Turkey.

出版信息

Acta Microbiol Immunol Hung. 2002;49(1):93-7. doi: 10.1556/AMicr.49.2002.1.9.

Abstract

Hepatitis A and hepatitis E are enteric transmitted viral diseases occurring in epidemic and sporadic forms especially in developing countries. Previous studies in Turkey showed that most residents are infected with HAV by the second decade of life. Since HEV is generally transmitted by the same route as HAV we conducted a community-based seroprevalence study for HAV and HEV infection in Ahatli area in Antalya, Turkey where socioeconomic conditions are low. Anti-HAV total immunoglobulin was tested by using a microparticle EIA (Axsym-Abbott Lab). Anti-HEV IgG was assayed by a micro ELISA method (Genelabs-Singapore). Of the 338 sera tested, 112 (33.1%) were positive for anti-HAV total antibody. Anti-HEV IgG was detected in three (0.89%) of the serum samples. Seropositivity rates of HAV in preschool and school children were 19.9% and 43.9% respectively (p < 0.001). No antibody to HEV was detected in preschool children, while the prevalence of anti-HEV IgG was 1.6% in children attending school. Our data showed that seroprevalence of anti-HAV is high among children samples but HEV infection appears to be relatively rare in pediatric age groups.

摘要

甲型肝炎和戊型肝炎是肠道传播的病毒性疾病,以流行和散发形式出现,尤其在发展中国家。土耳其先前的研究表明,大多数居民在20岁之前就感染了甲型肝炎病毒。由于戊型肝炎病毒通常与甲型肝炎病毒通过相同途径传播,我们在土耳其安塔利亚社会经济条件较差的阿特利地区开展了一项基于社区的甲型肝炎病毒和戊型肝炎病毒感染血清流行率研究。采用微粒酶免疫分析法(AxSYM - 雅培实验室)检测抗甲型肝炎病毒总免疫球蛋白。采用微量酶联免疫吸附测定法(吉诺实验室 - 新加坡)检测抗戊型肝炎病毒IgG。在检测的338份血清中,112份(33.1%)抗甲型肝炎病毒总抗体呈阳性。在3份(0.89%)血清样本中检测到抗戊型肝炎病毒IgG。学龄前儿童和学龄儿童的甲型肝炎病毒血清阳性率分别为19.9%和43.9%(p < 0.001)。学龄前儿童未检测到抗戊型肝炎病毒抗体,而在学龄儿童中抗戊型肝炎病毒IgG的患病率为1.6%。我们的数据表明,儿童样本中抗甲型肝炎病毒的血清流行率较高,但戊型肝炎病毒感染在儿童年龄组中似乎相对罕见。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验