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小学生戊型肝炎病毒血清流行率。

Seroprevalence of hepatitis e virus among primary school children.

机构信息

Nural Cevahir, Department of Medical Microbiology, School of Medicine, Pamukkale University, Denizli, Turkey.

Melek Demir, Department of Medical Microbiology, School of Medicine, Pamukkale University, Denizli, Turkey.

出版信息

Pak J Med Sci. 2013 Apr;29(2):629-32. doi: 10.12669/pjms.292.2821.

Abstract

To investigate the seroprevalence of anti-hepatitis E virus antibody among primary school children in the two different areas of Denizli, Turkey. Methodology : Anti-HEV antibodies were investigated in 185 primary school children (91 from rural areas and 94 from urban areas of Denizli). The children were divided into two age groups as seven-year old group and fourteen-year old group. Samples were tested for anti-HEV Ab by an enzyme-linked immunoassay. Results : A total of 23 primary school children were anti-HEV Ab positive, giving a prevalence of 12.4%. The seroprevalence rate was 13.1% in rural areas and 11.7% in urban areas. The difference in the seropositive rates was not statistically significant (p>0.05). Among 185 primary school children, Anti-HEV antibodies were positive 17 (18.1%) in seven-year old group, and 6 (6.6%) in fourteen-year old group. The difference in the seropositive rates was statistically significant (p<0.05). Conclusions : There was no association between the anti-HEV Ab and gender, socioeconomic level, parental educational level, rural or urban areas. Anti-HEV Ab seroprevalence was higher in seven-year old children than fourteen-year old children.

摘要

为了调查土耳其代尼兹利的两个不同地区的小学生中抗戊型肝炎病毒抗体的血清流行率。方法:在 185 名小学生(91 名来自农村地区,94 名来自代尼兹利的城市地区)中调查抗-HEV 抗体。将儿童分为 7 岁组和 14 岁组两个年龄组。通过酶联免疫吸附试验检测抗-HEV Ab。结果:共有 23 名小学生抗-HEV Ab 阳性,患病率为 12.4%。农村地区的血清阳性率为 13.1%,城市地区为 11.7%。血清阳性率差异无统计学意义(p>0.05)。在 185 名小学生中,7 岁组抗-HEV 抗体阳性 17 例(18.1%),14 岁组阳性 6 例(6.6%)。血清阳性率差异有统计学意义(p<0.05)。结论:抗-HEV Ab 与性别、社会经济水平、父母教育水平、农村或城市地区无关。7 岁儿童的抗-HEV Ab 血清流行率高于 14 岁儿童。

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