Wexler Randell K
Department of Family Medicine, Ohio State University College of Medicine and Public Health, Columbus 43201, USA.
Am Fam Physician. 2002 Jun 1;65(11):2307-14.
The body's ability to regulate core temperature depends on both host (internal) and environmental (external) factors. Although athletes are commonly thought to be most at risk for heat illnesses, children and the elderly are particularly vulnerable. Heat cramps, which are caused by fluid and electrolyte imbalances, are treated with massage, and fluid and electrolyte replacement. Heat exhaustion occurs both as water- and sodium-depleted types, with associated symptoms such as malaise, vomiting, and confusion. Treatment involves taking the affected person to a cool environment and replacing fluids and electrolytes if needed. In more serious cases, intravenous hydration may be necessary, although monitoring of serum sodium levels is important to prevent cerebral edema. If not treated promptly, heat exhaustion may evolve into heatstroke, a deadly form of heat illness. Heatstroke occurs in classic and exertional forms and is present when the core body temperature exceeds 40 degrees C (104 degrees F). The patient may experience cardiac arrhythmias, rhabdomyolysis, serum chemistry abnormalities, disseminated intravascular coagulation, and death. Heatstroke is a medical emergency that should be treated immediately with temperature-lowering techniques such as immersion in an ice bath or evaporative cooling. Fluid resuscitation is important but should be closely monitored, and renal function may need to be protected with mannitol and diuretics. It is important to be vigilant for heat illnesses because they occur insidiously but progress rapidly.
人体调节核心体温的能力取决于宿主(内部)和环境(外部)因素。尽管人们通常认为运动员最易患热相关疾病,但儿童和老年人尤其脆弱。热痉挛由液体和电解质失衡引起,通过按摩以及补充液体和电解质来治疗。热衰竭分为失水性和失盐性两种类型,伴有不适、呕吐和意识模糊等相关症状。治疗方法是将患者转移到凉爽的环境中,并在需要时补充液体和电解质。在更严重的情况下,可能需要静脉补液,不过监测血清钠水平对于预防脑水肿很重要。如果不及时治疗,热衰竭可能会演变成中暑,这是一种致命的热相关疾病。中暑有经典型和劳力型两种形式,当核心体温超过40摄氏度(104华氏度)时就会出现。患者可能会出现心律失常、横纹肌溶解、血清化学异常、弥散性血管内凝血,甚至死亡。中暑是一种医疗急症,应立即采用降温技术进行治疗,如浸入冰浴或蒸发冷却。液体复苏很重要,但应密切监测,可能需要用甘露醇和利尿剂来保护肾功能。对热相关疾病保持警惕很重要,因为它们发病隐匿但进展迅速。