产黄青霉中苄青霉素的积累位点。
The site of benzyl penicillin accumulation in Penicillium chrysogenum.
作者信息
Kuryłowicz W, Kurzatkowski W, Woźnicka W, Połowniak-Pracka H, Paszkiewicz A
出版信息
Zentralbl Bakteriol Naturwiss. 1979;134(8):721-32. doi: 10.1016/s0323-6056(79)80032-4.
Benzyl penicillin was localized in cells of Penicillium chrysogenum by means of enzymatical and immunological methods, enabling the determination of minute amounts of penicillin. The reactions were performed on ultrathin sections. They allow to determine the antibiotic inside of the cells. The results indicate that benzyl penicillin is present in the vesicles belonging to the Golgi apparatus. Benzyl penicillin is transported from the cytoplasm outside the cell membrane by the Golgi vesicles.
通过酶学和免疫学方法将苄青霉素定位在产黄青霉的细胞中，从而能够测定微量的青霉素。这些反应在超薄切片上进行。它们能够确定细胞内的抗生素。结果表明，苄青霉素存在于属于高尔基体的囊泡中。苄青霉素由高尔基体囊泡从细胞膜外的细胞质转运出去。
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