6-氧代哌啶-2-羧酸对产黄青霉PQ-96中L-赖氨酸抑制青霉素G生物合成的逆转作用
Reversion of L-lysine inhibition of penicillin G biosynthesis by 6-oxopiperidine-2-carboxylic acid in Penicillium chrysogenum PQ-96.
作者信息
Kurzatkowski W, Kurzatkowski J D, Filipek J, Solecka J, Kuryłowicz W
机构信息
State Institute of Hygiene, Warsaw, Poland.
出版信息
Appl Microbiol Biotechnol. 1990 Dec;34(3):397-8. doi: 10.1007/BF00170067.
PMID:1367520
Abstract
6-Oxopiperidine-2-carboxylic acid (OCA; cyclic alpha-aminoadipic acid) reverses the L-lysine inhibition of penicillin G production by Penicillium chrysogenum PQ-96. The reaction probably depends on the recovery of L-alpha-aminoadipic acid for penicillin G production from OCA.
摘要
6-氧代哌啶-2-羧酸（OCA；环状α-氨基己二酸）可逆转产黄青霉PQ-96中L-赖氨酸对青霉素G生产的抑制作用。该反应可能取决于从OCA中回收用于青霉素G生产的L-α-氨基己二酸。
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