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全血中猫血小板的自动分析,包括血小板计数、平均血小板体积和活化状态。

Automated analysis of feline platelets in whole blood, including platelet count, mean platelet volume, and activation state.

作者信息

Zelmanovic David, Hetherington Edward J.

机构信息

Bayer Diagnostics Division, 511 Benedict Ave., Tarrytown, NY 10591, USA.

出版信息

Vet Clin Pathol. 1998;27(1):2-9. doi: 10.1111/j.1939-165x.1998.tb01071.x.

DOI:10.1111/j.1939-165x.1998.tb01071.x
PMID:12075552
Abstract

A new whole-blood flow cytometric method has been developed for counting and sizing platelets in samples from cats, a species in which platelet and red blood cell sizes overlap significantly. The method is a modified version of the two-angle laser light scattering technology used by Bayer H*System hematology analyzers. The new method provided accurate platelet counts and mean platelet volumes (MPV, fl) for cats. The method also measured mean platelet component concentration (MPC, g/dl), a parameter which was shown to be sensitive to platelet activation state, and which decreased in value as activation progressed.

摘要

已经开发出一种新的全血流式细胞术方法,用于对猫的样本中的血小板进行计数和大小测定,猫的血小板和红细胞大小存在显著重叠。该方法是拜耳H*系统血液分析仪所使用的双角度激光散射技术的改进版本。新方法能够为猫提供准确的血小板计数和平均血小板体积(MPV,飞升)。该方法还能测量平均血小板成分浓度(MPC,克/分升),这一参数被证明对血小板活化状态敏感,且随着活化进展其值会降低。

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