Mortara M, Donna A
Minerva Med. 1975 Dec 15;66(86):4648-58.
Inflammation of the hypothalamus, consisting of perivasal parvicellular sleeves between the paraventricular nucleus rostrally, the mamillary nuclei caudally, 3rd ventricle wall below the sulcus, medially and o sagittal plane taken a little beyond the column of the fornix laterally--i.e. in the space shown to include the hypophysothyrotropic structures by experimental physiopathology--was observed in a woman with endemic goitre. Reference is made to a similar finding in goitrous dogs from enzootic areas of Piedmon. Epidemiological and clinical considerations are put forwary for the view that endemic goitre is responsible for primary cerebral damage, perhaps of encephalitic origin.
在一名患有地方性甲状腺肿的女性中，观察到下丘脑炎症，其范围包括：在前方室旁核与后方乳头体核之间的血管周围小细胞套，在沟下方的第三脑室壁，在内侧以及在矢状面外侧略超出穹窿柱的区域——即，在实验生理病理学显示包含促甲状腺垂体结构的空间内。文中提到在皮埃蒙特动物疫病流行地区的甲状腺肿犬中也有类似发现。对于地方性甲状腺肿可能导致原发性脑损伤（可能起源于脑炎）这一观点，提出了流行病学和临床方面的考量。
