Sibilia J, Limbach F-X
Rheumatology Department, University Hospital of Strasbourg, France.
Ann Rheum Dis. 2002 Jul;61(7):580-7. doi: 10.1136/ard.61.7.580.
Microbes reach the synovial cavity either directly during bacteraemia or by transport within lymphoid cells or monocytes. This may stimulate the immune system excessively, triggering arthritis. Some forms of ReA correspond to slow infectious arthritis due to the persistence of microbes and some to an infection triggered arthritis linked to an extra-articular site of infection.
微生物可在菌血症期间直接进入滑膜腔,或通过在淋巴细胞或单核细胞内运输进入。这可能会过度刺激免疫系统,引发关节炎。某些形式的反应性关节炎相当于由于微生物持续存在导致的缓慢感染性关节炎,还有一些则相当于与关节外感染部位相关的感染引发的关节炎。