Gruszczyńska Joanna, Charon Krystyna M, Swiderek Wiesław, Sawera Milena
Department of Genetics and Animal Breeding, Warsaw Agricultural University, Warszawa, Poland.
J Appl Genet. 2002;43(2):217-22.
Our study aimed at comparative analysis of microsatellite polymorphism in locus OMHC1 (MHC Class I) in Polish Heath Sheep and Polish Lowland Sheep (Zelazna variety). The study was conducted on 100 ewes of each breed. We identified 13 alleles of the gene in Polish Heath Sheep and 9 in Polish Lowland Sheep. We found marked differences in frequency of OMHC1 alleles between both breeds. The heterozygosity coefficient and PIC, amounting to 0.79 and 0.77 for Polish Heath Sheep, and 0.82 and 0.80 for Polish Lowland Sheep, respectively, suggest considerable variability in both breeds. Additionally, the values of both coefficients indicate that OMHC1 locus can be used as a genetic marker.
我们的研究旨在比较分析波兰 Heath 羊和波兰低地羊（泽拉兹纳品种）的 OMHC1 位点（MHC I 类）中的微卫星多态性。对每个品种的 100 只母羊进行了研究。我们在波兰 Heath 羊中鉴定出该基因的 13 个等位基因，在波兰低地羊中鉴定出 9 个。我们发现两个品种之间 OMHC1 等位基因的频率存在显著差异。波兰 Heath 羊的杂合度系数和 PIC 分别为 0.79 和 0.77，波兰低地羊分别为 0.82 和 0.80，这表明两个品种都有相当大的变异性。此外，两个系数的值表明 OMHC1 位点可作为遗传标记。
