Dickel H, Bruckner T, Bernhard-Klimt C, Koch T, Scheidt R, Diepgen T L
Department of Clinical Social Medicine, Centre of Occupational and Environmental Dermatology, University Hospital of Heidelberg, Heidelberg, Germany.
Contact Dermatitis. 2002 Apr;46(4):197-206. doi: 10.1034/j.1600-0536.2002.460403.x.
Occupational skin disease (OSD) is a significant public health concern. To keep OSDs under surveillance, a register of OSDs (BKH-S) was implemented in 1999 in the Saarland, FRG. We conducted a population-based register study to analyse all initial reports of OSDs reported to the BKH-S. 336 cases were prospectively assessed from July 1999 to June 2001. In 78% (n = 263) of the cases an occupational cause for the skin disease was stated, 91% (n = 240) of which fell within 16 occupational groups. This is equivalent to 6.8 cases per 10,000 workers per year within these occupational groups. Notably, young age groups (median age 35 years) were affected with a female predominance. The most frequent final diagnosis was irritant contact dermatitis (75%) followed by allergic contact dermatitis (34%) and atopic dermatitis (19%). The overall prevalence of occupationally relevant delayed-type reactors was 21% and of immediate-type reactors 17%. Work-related delayed-type sensitizations to potassium dichromate (n = 8) and immediate-type sensitizations to natural rubber latex (n = 11) were the most frequently observed. Questionnaire results showed frequent occupational skin contact with wet work (59%), detergents (48%), and disinfectants (38%). The second valid surveillance scheme for OSD in the FRG has been introduced and can be made available for further analysis.
职业性皮肤病(OSD)是一个重大的公共卫生问题。为了对职业性皮肤病进行监测,1999年在德意志联邦共和国萨尔州实施了职业性皮肤病登记册(BKH-S)。我们进行了一项基于人群的登记研究,以分析向BKH-S报告的所有职业性皮肤病初始报告。1999年7月至2001年6月对336例病例进行了前瞻性评估。在78%(n = 263)的病例中确定了皮肤病的职业病因,其中91%(n = 240)属于16个职业类别。这相当于这些职业类别中每年每10000名工人中有6.8例病例。值得注意的是,年轻年龄组(中位年龄35岁)受到影响,女性占主导。最常见的最终诊断是刺激性接触性皮炎(75%),其次是过敏性接触性皮炎(34%)和特应性皮炎(19%)。职业相关迟发型反应者的总体患病率为21%,速发型反应者为17%。最常观察到的与工作相关的对重铬酸钾的迟发型致敏(n = 8)和对天然橡胶乳胶的速发型致敏(n = 11)。问卷调查结果显示,经常在工作中接触湿作业(59%)、洗涤剂(48%)和消毒剂(38%)。德意志联邦共和国第二个有效的职业性皮肤病监测方案已经推出,可用于进一步分析。