感染性梅毒的异性传播疫情：流行病学与民族志分析及其对防控的启示
Heterosexual outbreak of infectious syphilis: epidemiological and ethnographic analysis and implications for control.
作者信息
Patrick D M, Rekart M L, Jolly A, Mak S, Tyndall M, Maginley J, Wong E, Wong T, Jones H, Montgomery C, Brunham R C
机构信息
University of British Columbia Centre for Disease Control, Vancouver, Canada.
出版信息
Sex Transm Infect. 2002 Apr;78 Suppl 1(Suppl 1):i164-9. doi: 10.1136/sti.78.suppl_1.i164.
This study describes the epidemiology and ethnography of an outbreak of infectious syphilis in Vancouver, British Columbia. Between 1996 and 1999, British Columbias's rate of infectious syphilis rose from 0.5 to 3.4 per 100,000, with a dense concentration of cases among sex trade workers, their clients, and street-involved people in the downtown eastside area of Vancouver. Sexual networks were imported cases with secondary spread (dyads and triads), large densely connected dendritic networks of sex trade workers and clients, or occasional starburst networks among gay men. Only 232 of 429 partners were documented as having been treated (54% of those named, or 0.9 per case). The geographical and demographic concentration of this outbreak led to consideration of a programme of focused mass treatment with single dose azithromycin.
本研究描述了加拿大不列颠哥伦比亚省温哥华市传染性梅毒暴发的流行病学和人种学情况。1996年至1999年间，不列颠哥伦比亚省传染性梅毒发病率从每10万人0.5例升至3.4例，病例密集集中在温哥华市中心东区的性交易工作者、她们的客户以及街头流浪人员中。性传播网络包括有二代传播（二元组和三元组）的输入性病例、性交易工作者与客户之间紧密相连的大型树状网络，或男同性恋者中偶尔出现的星爆网络。在429名性伴侣中，仅有232人记录接受过治疗（占提及人数的54%，即每例0.9人）。此次疫情在地理和人口方面的集中情况促使人们考虑实施一项采用单剂量阿奇霉素进行集中大规模治疗的方案。
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