英国谢菲尔德近期梅毒疫情的特征描述以及将接触者追踪作为一种控制方法的评估。
The characterisation of a recent syphilis outbreak in Sheffield, UK, and an evaluation of contact tracing as a method of control.
作者信息
Singh Selena, Bell Gill, Talbot Martin
机构信息
The Medical School, University of Sheffield, Beech Hill Road, Sheffield 10, UK.
出版信息
Sex Transm Infect. 2007 Jun;83(3):193-9. doi: 10.1136/sti.2006.022145. Epub 2006 Dec 6.
OBJECTIVE
To explore the factors around and the success of contact-tracing in a recent major outbreak of infectious syphilis in Sheffield, and to evaluate the effectiveness of it, our hitherto standard strategy of control.
METHOD
Retrospective chart review
RESULTS
Over a period of 18 months, an outbreak of 21 cases was, on closer inspection, the result of several, discrete "micro" outbreaks in different groups. Two major patterns emerged, a relatively straightforward and more accessible cluster in heterosexual persons (a "spread" network), and more sporadic, "starburst" networks in men who have sex with men.
CONCLUSION
Our traditional method of control, contact-tracing, was seen to be most effective in the spread network in heterosexuals. In the face of an apparent outbreak, clinicians should explore the nature and parameters of their local epidemic and engage a mixture of control methods. These may include, but not excusively so, contact-tracing to interrupt transmission by case-finding and by treatment.
目的
探究近期谢菲尔德梅毒大暴发中接触者追踪的相关因素及成效，并评估我们一直以来的标准防控策略——接触者追踪的有效性。
方法
回顾性病历审查
结果
在18个月的时间里，经仔细调查发现，21例病例的暴发是由不同群体中几次分散的“微型”暴发所致。出现了两种主要模式，一种是异性恋者中相对直接且更容易接触到的聚集性病例（“传播”网络），另一种是男男性行为者中更为零散的“星爆”网络。
结论
我们传统的防控方法——接触者追踪，在异性恋者的传播网络中最为有效。面对明显的疫情暴发，临床医生应探究当地疫情的性质和参数，并采用多种防控方法。这些方法可能包括但不限于通过病例发现和治疗进行接触者追踪以中断传播。
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