Sobel J D, Lundstrom T
Division of Infectious Diseases, Wayne State University School of Medicine, Harper Hospital, Detroit, MI 48201, USA.
Curr Urol Rep. 2001 Aug;2(4):321-5. doi: 10.1007/s11934-001-0071-3.
The distinction between Candida colonization of the urinary tract and infection is often blurred. Asymptomatic candiduria is particularly common in catheterized intensive care unit patients. To date, few studies have addressed the appropriate treatment regimens for candiduria. Fluconazole has become a mainstay of therapy; however, when to treat, whom to treat, and how long to treat are still largely unanswered questions. Asymptomatic nosocomial candiduria infrequently requires treatment intervention because morbidity is low and ascending infection and candidemia are rare complications. An understanding of the anatomic site of infection drives treatment decisions. More research is needed to define diagnostic criteria and therapeutic pathways. This review attempts to summarize the diagnosis and management of candiduria.
泌尿道念珠菌定植与感染之间的区别常常模糊不清。无症状性念珠菌尿在留置导尿管的重症监护病房患者中尤为常见。迄今为止,很少有研究探讨念珠菌尿的恰当治疗方案。氟康唑已成为治疗的主要药物;然而,何时治疗、治疗何人以及治疗多久在很大程度上仍是未解决的问题。无症状性医院内念珠菌尿很少需要治疗干预,因为发病率低,上行性感染和念珠菌血症是罕见的并发症。对感染解剖部位的了解有助于做出治疗决策。需要更多研究来确定诊断标准和治疗途径。本综述试图总结念珠菌尿的诊断和管理。