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[念珠菌尿症:临床与治疗方法]

[Candiduria: a clinical and therapeutic approach].

作者信息

Colombo Arnaldo Lopes, Guimarães Thaís

机构信息

Universidade Federal de São Paulo, São Paulo, SP, Brasil.

出版信息

Rev Soc Bras Med Trop. 2007 May-Jun;40(3):332-7. doi: 10.1590/s0037-86822007000300016.

Abstract

Candiduria remains a controversial issue for clinicians once that it may represent a broad variety of possibilities including colonization, local or systemic infection. We will discuss the epidemiology, diagnosis and treatment of candiduria in different settings of patients, including renal transplant recipients. Definitions on therapy are mostly based on epidemiological and clinical data. Once antifungal therapy is required the following antifungal treatment may be used: intravenous amphotericin B, bladder irrigation with amphotericin B or fluconazole. Blood cultures may be required in patients with candiduria and high risk for developing hematogenous infection. Removal of the urinary catheter must be considered in order to avoid persistent candiduria and recurrence.

摘要

念珠菌尿症对临床医生来说仍是一个有争议的问题,因为它可能代表多种情况,包括定植、局部或全身感染。我们将讨论不同患者群体中念珠菌尿症的流行病学、诊断和治疗,包括肾移植受者。治疗的定义大多基于流行病学和临床数据。一旦需要抗真菌治疗,可采用以下抗真菌治疗方法:静脉注射两性霉素B、用两性霉素B或氟康唑进行膀胱冲洗。念珠菌尿症且有发生血源性感染高风险的患者可能需要进行血培养。必须考虑拔除导尿管,以避免念珠菌尿症持续存在和复发。

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