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[念珠菌尿症:临床与治疗方法]

[Candiduria: a clinical and therapeutic approach].

作者信息

Colombo Arnaldo Lopes, Guimarães Thaís

机构信息

Universidade Federal de São Paulo, São Paulo, SP, Brasil.

出版信息

Rev Soc Bras Med Trop. 2007 May-Jun;40(3):332-7. doi: 10.1590/s0037-86822007000300016.

DOI:10.1590/s0037-86822007000300016
PMID:17653471
Abstract

Candiduria remains a controversial issue for clinicians once that it may represent a broad variety of possibilities including colonization, local or systemic infection. We will discuss the epidemiology, diagnosis and treatment of candiduria in different settings of patients, including renal transplant recipients. Definitions on therapy are mostly based on epidemiological and clinical data. Once antifungal therapy is required the following antifungal treatment may be used: intravenous amphotericin B, bladder irrigation with amphotericin B or fluconazole. Blood cultures may be required in patients with candiduria and high risk for developing hematogenous infection. Removal of the urinary catheter must be considered in order to avoid persistent candiduria and recurrence.

摘要

念珠菌尿症对临床医生来说仍是一个有争议的问题,因为它可能代表多种情况,包括定植、局部或全身感染。我们将讨论不同患者群体中念珠菌尿症的流行病学、诊断和治疗,包括肾移植受者。治疗的定义大多基于流行病学和临床数据。一旦需要抗真菌治疗,可采用以下抗真菌治疗方法:静脉注射两性霉素B、用两性霉素B或氟康唑进行膀胱冲洗。念珠菌尿症且有发生血源性感染高风险的患者可能需要进行血培养。必须考虑拔除导尿管,以避免念珠菌尿症持续存在和复发。

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1
[Candiduria: a clinical and therapeutic approach].[念珠菌尿症:临床与治疗方法]
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引用本文的文献

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Identification and antifungal susceptibility of Candida species isolated from the urine of patients in a university hospital in Brazil.从巴西一家大学医院患者尿液中分离出的念珠菌属的鉴定及抗真菌药敏性
Rev Inst Med Trop Sao Paulo. 2017 Dec 21;59:e75. doi: 10.1590/S1678-9946201759075.
2
Brazilian guidelines for the management of candidiasis - a joint meeting report of three medical societies: Sociedade Brasileira de Infectologia, Sociedade Paulista de Infectologia and Sociedade Brasileira de Medicina Tropical.巴西念珠菌病管理指南——三个医学协会的联合会议报告:巴西传染病学会、圣保罗传染病学会和巴西热带医学学会。
Braz J Infect Dis. 2013 May-Jun;17(3):283-312. doi: 10.1016/j.bjid.2013.02.001. Epub 2013 May 18.
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Chromogenic medium for direct susceptibility testing of Candida spp. isolated from urine.
用于尿液分离念珠菌属直接药敏试验的显色培养基。
Mycopathologia. 2011 Aug;172(2):125-30. doi: 10.1007/s11046-011-9407-9. Epub 2011 Mar 3.
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Prospective study of urinary tract infection surveillance after kidney transplantation.肾移植后尿路感染监测的前瞻性研究。
BMC Infect Dis. 2010 Aug 19;10:245. doi: 10.1186/1471-2334-10-245.