Miyata Yuki, Sugiura Chika, Kobayashi Yuki, Hagiwara Mitsuru, Sugita Mamoru
Center for Gene Research, Nagoya University, Nagoya 464-8602, Japan.
Biochim Biophys Acta. 2002 Jul 19;1576(3):346-9. doi: 10.1016/s0167-4781(02)00346-9.
The rps14 transcript is edited in the moss Physcomitrella patens chloroplast by a C-to-U transition, to create a translation initiation codon, AUG. The efficiency of RNA editing was low, with approximately 20% of rps14 transcripts edited. This suggests that the translation of rps14 mRNA is strictly regulated by RNA editing. This is the first report of RNA editing in P. patens and the creation of a translation initiation codon in rps14 mRNA in chloroplasts.
在小立碗藓叶绿体中，rps14转录本通过C到U的转变进行编辑，从而产生翻译起始密码子AUG。RNA编辑效率较低，约20%的rps14转录本被编辑。这表明rps14 mRNA的翻译受到RNA编辑的严格调控。这是关于小立碗藓RNA编辑以及叶绿体中rps14 mRNA产生翻译起始密码子的首次报道。
