Valdimarsdóttir U, Helgason A R, Fürst C-J, Adolfsson J, Steineck G
Department of Clinical Cancer Epidemiology, Inst. Oncology-Pathology, Karolinska Institute, Box 4402, 10268 Stockholm, Sweden.
Br J Cancer. 2002 May 20;86(10):1540-5. doi: 10.1038/sj.bjc.6600271.
We investigated if a cancer patient's unrelieved symptoms during the last 3 months of life increase the risk of long-term psychological morbidity of the surviving partner. All women (n=506) living in Sweden under 80 years of age, who lost their husband/partner owing to cancer of the prostate in 1996 or of the urinary bladder in 1995 or 1996 were asked to answer an anonymous postal questionnaire, 2-4 years after their loss. The widows' psychological morbidity was associated with the patient's unrelieved mental symptoms. When the patient was perceived to have been very anxious during last three months of life (compared to no observed symptoms) the relative risks for the widows' psychological morbidity were: 2.5 (1.4-4.3) for depression and 3.4 (1.4-8.2) for anxiety. When comparing reports of the patient's pain (much vs no), the relative risks were 0.8 (0.5-1.2) for widowhood depression, and 0.8 (0.4-1.7) for widowhood anxiety. The patients were found to have had adequate access to physical pain control but poor access to psychological symptom control. Efficiency in diagnosing and treating psychological complications of terminally ill cancer patients may not only improve their quality of life but possibly also prevent long-term psychological morbidity of their surviving partners.
我们调查了癌症患者在生命最后3个月未缓解的症状是否会增加其在世伴侣长期出现心理疾病的风险。所有年龄在80岁以下、于1996年因前列腺癌或在1995年或1996年因膀胱癌失去丈夫/伴侣、居住在瑞典的女性(n = 506),在丧偶2至4年后被要求回答一份匿名邮寄问卷。寡妇的心理疾病与患者未缓解的精神症状有关。当患者在生命的最后三个月被认为非常焦虑时(与未观察到症状相比),寡妇出现心理疾病的相对风险为:抑郁症为2.5(1.4 - 4.3),焦虑症为3.4(1.4 - 8.2)。比较患者疼痛报告(疼痛剧烈与无疼痛)时,丧偶抑郁症的相对风险为0.8(0.5 - 1.2),丧偶焦虑症的相对风险为0.8(0.4 - 1.7)。结果发现患者在身体疼痛控制方面有足够的途径,但在心理症状控制方面途径较少。对晚期癌症患者心理并发症的诊断和治疗效率不仅可能改善他们的生活质量,还可能预防其在世伴侣的长期心理疾病。