生死攸关的事。

A matter of life and death.

作者信息

Green Douglas R, Evan Gerard I

机构信息

La Jolla Institute for Allergy and Immunology, 10355 Science Center Drive, San Diego, California 92121, USA.

出版信息

Cancer Cell. 2002 Feb;1(1):19-30. doi: 10.1016/s1535-6108(02)00024-7.

DOI:10.1016/s1535-6108(02)00024-7

PMID:12086884

Abstract

We propose that deregulation of proliferation, together with a reduction in apoptosis, creates a platform that is both necessary and can be sufficient for cancer. The secondary traits of diverse neoplasms are a consequence of cell proliferation, tissue expansion, and other outcomes of this platform.

摘要

我们认为，增殖失控以及细胞凋亡减少共同创建了一个对癌症而言既必要又充分的平台。各种肿瘤的次要特征是细胞增殖、组织扩张以及该平台的其他结果所导致的。