Nephrol Dial Transplant. 2002;17 Suppl 4:30-1. doi: 10.1093/ndt/17.suppl_4.30.
Immunosuppressive therapies, especially corticosteroids and anticalcineurin inhibitors; contribute to the prevalence of cardiovascular risk factors, such as arterial hypertension, hyperlipidaemia and hyperglycaemia, and this effect is dose dependent. Reduction of the dose, withdrawal and/or switching to another drug could be useful to control these risk factors.
免疫抑制疗法,尤其是皮质类固醇和钙调神经磷酸酶抑制剂,会导致动脉高血压、高脂血症和高血糖等心血管危险因素的流行,且这种影响呈剂量依赖性。降低剂量、停药和/或换用另一种药物可能有助于控制这些危险因素。