Humlová Z
Ustav patologické fyziologie 1. lékarské fakulty Univerzity Karlovy, U nemocnice 5, 128 53 Praha 2, Czech Republic.
Sb Lek. 2001;102(3):329-39.
Viruses are obligatory intracellular parasites, which differ in their structure and strategy of replication. The establishment of an antiviral state in uninfected cells and the elimination of virally infected cells are critical tasks in the host defence. Against the extensive array of immune modalities, viruses have successfully learned how to manipulate host immune control mechanisms. The study of viral strategies of immune evasion can provide insights into host-virus interactions and also illuminates essential functions of the immune system.
病毒是专性细胞内寄生虫，其复制结构和策略各不相同。在未感染的细胞中建立抗病毒状态以及清除病毒感染的细胞是宿主防御中的关键任务。面对广泛的免疫方式，病毒已成功学会如何操纵宿主免疫控制机制。对病毒免疫逃逸策略的研究可以深入了解宿主与病毒的相互作用，也有助于阐明免疫系统的基本功能。
