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膀胱恶性副神经节瘤。病例报告。

Malignant paraganglioma of the urinary bladder. A case report.

作者信息

Ansari M S, Goel A, Goel S, Durairajan L N, Seth A

机构信息

Department of Urology and Pathology, All India Institute of Medical Sciences, New Delhi.

出版信息

Int Urol Nephrol. 2001;33(2):343-5. doi: 10.1023/a:1015253427161.

Abstract

Paraganglioma (pheochromocytoma) is probably the most fascinating of all tumors as it can present with a wide range of clinical manifestations. Paraganglioma of the urinary bladder is one of the rare tumors and constitute less than 10% of all bladder tumors. The common presentation of paraganglioma of the urinary bladder is painless haematuria, headache, palpitation and anxiety. Malignancy is uncommon and no histological feature is characteristic of malignancy. Invasion of adjacent organs or metastasis to the lymph nodes is the only criteria to suggest malignancy. In the presence of proven metastasis radical cystectomy with pelvic lymphadenectomy is recommended. In the present case the tumor was arising from anterior wall of the bladder away from the bladder neck and that in a large capacity bladder it was possible to get a wide margin for partial cystectomy along with bilateral pelvic lymphadenectomy without violating the oncological principles. At a follow up of two years there is no evidence of recurrence of tumor.

摘要

副神经节瘤(嗜铬细胞瘤)可能是所有肿瘤中最引人入胜的,因为它可表现出广泛的临床表现。膀胱副神经节瘤是一种罕见肿瘤,占所有膀胱肿瘤的比例不到10%。膀胱副神经节瘤的常见表现为无痛性血尿、头痛、心悸和焦虑。恶性情况并不常见,且没有恶性的组织学特征。侵犯相邻器官或转移至淋巴结是提示恶性的唯一标准。在证实有转移的情况下,建议行根治性膀胱切除术及盆腔淋巴结清扫术。在本病例中,肿瘤起源于膀胱前壁远离膀胱颈处,且在大容量膀胱的情况下,有可能在不违反肿瘤学原则的前提下,进行部分膀胱切除术并双侧盆腔淋巴结清扫术时获得较宽的切缘。在两年的随访中,没有肿瘤复发的证据。

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