胰腺弹性蛋白酶从人血红蛋白中释放出血啡肽-5。
Release of hemorphin-5 from human hemoglobin by pancreatic elastase.
作者信息
Jinsmaa Yunden, Yoshikawa Masaaki
机构信息
Graduate School of Agriculture, Kyoto University, Uji, Japan.
出版信息
Biosci Biotechnol Biochem. 2002 May;66(5):1130-2. doi: 10.1271/bbb.66.1130.
PMID:12092829
Abstract
Opioid peptide hemorphin-5 (YPWTQ) was released from human hemoglobin by the action of pancreatic elastase. V-hemorphin-5 (VYPWTQ) was also released under the same conditions. The amount of hemorphin-5 was about 1/10 that of V-hemorphin-5. This is the first report showing release of hemorphin-5 only by the action of one enzyme.
摘要
阿片肽类的血啡肽-5（YPWTQ）通过胰弹性蛋白酶的作用从人血红蛋白中释放出来。在相同条件下，缬氨酸-血啡肽-5（VYPWTQ）也会释放出来。血啡肽-5的量约为缬氨酸-血啡肽-5的1/10。这是第一份表明仅通过一种酶的作用就能释放血啡肽-5的报告。
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