Al-Haddad Syed A, Kirollos Ramez
Walton Centre for Neurology and Neurosurgery, Liverpool, UK.
Ann R Coll Surg Engl. 2002 May;84(3):196-200.
Many changes and improvement have taken place in the management of head injured patients in the last 20 years. There have been few recent studies analysing the overall outcomes including early complications of depressed skull fractures. The aim of our study was, therefore, to examine the factors influencing the surgical outcome of patients with depressed skull fractures.
We reviewed case notes of 73 consecutive surgically treated depressed skull fractures during the period from 1 January 1994 to 31 December 1998 admitted to the Walton Centre for Neurology and Neurosurgery, Liverpool.
There was a male preponderance of 9:1. Alleged assault was the most common cause of depressed skull fractures followed by road traffic accidents. Postoperative infection rate was 8.2%. More than 80% of patients received prophylactic antibiotics. We failed to show any statistically significant association between the use of antibiotics and reduction of the rate of infection. However, prevalence of infection was significantly associated with brain contusion, low GCS score and dural tear (P < 0.05). Prevalence of early post-traumatic epilepsy was 12.3%. No patients received prophylactic anticonvulsants. There was no significant association between dural tear and prevalence of post-traumatic epilepsy. Mortality rate was 1.4%.
Paediatric populations have better outcome; 7 out of 10 patients in this series progressed to full recovery. Use of prophylactic antibiotics did not reduce the infection rate. Presence of dural tear was not associated with an increase risk of post-traumatic epilepsy.
在过去20年中,颅脑损伤患者的管理发生了许多变化和改进。最近很少有研究分析包括凹陷性颅骨骨折早期并发症在内的总体结果。因此,我们研究的目的是探讨影响凹陷性颅骨骨折患者手术结果的因素。
我们回顾了1994年1月1日至1998年12月31日期间连续收治于利物浦沃尔顿神经外科中心的73例接受手术治疗的凹陷性颅骨骨折患者的病历。
男性与女性的比例为9:1。据称的袭击是凹陷性颅骨骨折最常见的原因,其次是道路交通事故。术后感染率为8.2%。超过80%的患者接受了预防性抗生素治疗。我们未能显示抗生素的使用与感染率降低之间存在任何统计学上的显著关联。然而,感染的发生率与脑挫伤、低格拉斯哥昏迷评分和硬脑膜撕裂显著相关(P < 0.05)。创伤后早期癫痫的发生率为12.3%。没有患者接受预防性抗惊厥药物治疗。硬脑膜撕裂与创伤后癫痫的发生率之间没有显著关联。死亡率为1.4%。
儿童患者的预后较好;本系列中十分之七的患者完全康复。预防性使用抗生素并未降低感染率。硬脑膜撕裂的存在与创伤后癫痫风险增加无关。